The role of sub-hippocampal versus hippocampal ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
The role of sub-hippocampal versus hippocampal regions in bitemporal lobe epilepsies
Auteur(s) :
Aubert, Sandrine [Auteur]
Bonini, Francesca [Auteur]
Curot, Jonathan [Auteur]
Valton, Luc [Auteur]
Szurhaj, William [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Derambure, Philippe [Auteur]
Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177
Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 [M2SV]
Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 [M2SV]
Rheims, Sylvain [Auteur]
Ryvlin, Philippe [Auteur]
Wendling, Fabrice [Auteur]
Mcgonigal, Aileen [Auteur]
Trebuchon, Agnes [Auteur]
Bartolomei, Fabrice [Auteur]
Bonini, Francesca [Auteur]
Curot, Jonathan [Auteur]
Valton, Luc [Auteur]
Szurhaj, William [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Derambure, Philippe [Auteur]
Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177
Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 [M2SV]
Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 [M2SV]
Rheims, Sylvain [Auteur]
Ryvlin, Philippe [Auteur]
Wendling, Fabrice [Auteur]
Mcgonigal, Aileen [Auteur]
Trebuchon, Agnes [Auteur]
Bartolomei, Fabrice [Auteur]
Titre de la revue :
Clinical neurophysiology . official journal of the International Federation of Clinical Neurophysiology
Nom court de la revue :
Clin. Neurophysiol.
Numéro :
127
Pagination :
2992-2999
Date de publication :
2016-09-01
ISSN :
1388-2457
Mot(s)-clé(s) en anglais :
Bilateral temporal epilepsy
Surgery
Epileptogenicity Index
Entorhinal cortex
SEEG
Surgery
Epileptogenicity Index
Entorhinal cortex
SEEG
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
OBJECTIVE: We aimed at better delineating the functional anatomical organization of bitemporal lobe epilepsy.
METHODS: We studied the epileptogenic zone (EZ) by quantifying the epileptogenicity of brain structures explored ...
Lire la suite >OBJECTIVE: We aimed at better delineating the functional anatomical organization of bitemporal lobe epilepsy. METHODS: We studied the epileptogenic zone (EZ) by quantifying the epileptogenicity of brain structures explored by depth electrodes in patients investigated by stereoelectroencephalography (SEEG). We compared 15 patients with bilateral mesial temporal lobe epilepsy (BTLE) and 15 patients with unilateral mesial temporal lobe epilepsy (UTLE). This quantification was performed using the 'Epileptogenicity Index' (EI). RESULTS: Age at epilepsy onset, and epilepsy duration, were not statistically different in both groups. UTLE patients more frequently displayed maximal epileptogenicity in hippocampal structures, whereas BTLE patients had maximal values in subhippocampal areas (entorhinal cortex, temporal pole, parahippocampal cortex). CONCLUSIONS: Our results suggest different organization of the EZ in the two groups. CONCLUSIONS: BTLE was associated with more involvement of subhippocampal regions, a result in agreement with known anatomical connections between the two temporal lobes.Lire moins >
Lire la suite >OBJECTIVE: We aimed at better delineating the functional anatomical organization of bitemporal lobe epilepsy. METHODS: We studied the epileptogenic zone (EZ) by quantifying the epileptogenicity of brain structures explored by depth electrodes in patients investigated by stereoelectroencephalography (SEEG). We compared 15 patients with bilateral mesial temporal lobe epilepsy (BTLE) and 15 patients with unilateral mesial temporal lobe epilepsy (UTLE). This quantification was performed using the 'Epileptogenicity Index' (EI). RESULTS: Age at epilepsy onset, and epilepsy duration, were not statistically different in both groups. UTLE patients more frequently displayed maximal epileptogenicity in hippocampal structures, whereas BTLE patients had maximal values in subhippocampal areas (entorhinal cortex, temporal pole, parahippocampal cortex). CONCLUSIONS: Our results suggest different organization of the EZ in the two groups. CONCLUSIONS: BTLE was associated with more involvement of subhippocampal regions, a result in agreement with known anatomical connections between the two temporal lobes.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Date de dépôt :
2019-11-27T13:37:26Z