Title :

Pre-frontal-insular-cerebellar modifications correlate with disgust feeling blunting after subthalamic stimulation: a positron emission tomography study in parkinson''s disease

Author(s) :

Ory, Sophie [Auteur]
Le Jeune, Florence [Auteur]
Haegelen, Claire [Auteur]
Vicente, Siobhan [Auteur]
Philippot, Pierre [Auteur]
Dondaine, Thibaut [Auteur]
Jannin, Pierre [Auteur]
Drapier, Sophie [Auteur]
Drapier, Dominique [Auteur]
Sauleau, Paul [Auteur]
Verin, Marc [Auteur]
Peron, Julie [Auteur]

Journal title :

Journal of Neuropsychology

Abbreviated title :

J. Neuropsychol.

Volume number :

11

Pages :

378-395

Publication date :

2017-09-01

ISSN :

1748-6645

English keyword(s) :

orbitofrontal cortex
subthalamic nucleus
(18)[F]fluorodeoxyglucose positron emission tomography
feelings
emotion
insula
cerebellum

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Subthalamic nucleus (STN) deep brain stimulation (DBS) has recently advanced our understanding of the major role played by this basal ganglion in human emotion. Research indicates that STN DBS can induce modifications in ...
Show more >Subthalamic nucleus (STN) deep brain stimulation (DBS) has recently advanced our understanding of the major role played by this basal ganglion in human emotion. Research indicates that STN DBS can induce modifications in all components of emotion, and neuroimaging studies have shown that the metabolic modifications correlated with these emotional disturbances following surgery are both task- and sensory input-dependent. Nevertheless, to date, these modifications have not been confirmed for all emotional components, notably subjective emotional experience, or feelings. To identify the neural network underlying the modification of feelings following STN DBS, we assessed 16 patients with Parkinson's disease before and after surgery, using both subjective assessments of emotional experience and 1818Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T13:37:32Z