Antiplatelet therapy after noncardioembolic stroke
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Antiplatelet therapy after noncardioembolic stroke
Auteur(s) :
Greving, Jacoba P. [Auteur]
Diener, Hans-Christoph [Auteur]
Reitsma, Johannes B. [Auteur]
Bath, Philip M. W. [Auteur]
Csiba, Laszlo [Auteur]
Hacke, Werner [Auteur]
Kappelle, L. Jaap [Auteur]
Koudstaal, Peter J. [Auteur]
LEYS, Didier [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Mas, Jean-Louis [Auteur]
Sacco, Ralph L. [Auteur]
Algra, Ale [Auteur]
Diener, Hans-Christoph [Auteur]
Reitsma, Johannes B. [Auteur]
Bath, Philip M. W. [Auteur]
Csiba, Laszlo [Auteur]
Hacke, Werner [Auteur]
Kappelle, L. Jaap [Auteur]
Koudstaal, Peter J. [Auteur]
LEYS, Didier [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Mas, Jean-Louis [Auteur]
Sacco, Ralph L. [Auteur]
Algra, Ale [Auteur]
Titre de la revue :
Stroke
Nom court de la revue :
Stroke
Pagination :
STROKEAHA118024497
Date de publication :
2019-06-10
ISSN :
1524-4628
Mot(s)-clé(s) en anglais :
efficacy
antiplatelet agents
myocardial infarction
secondary prevention
stroke
antiplatelet agents
myocardial infarction
secondary prevention
stroke
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background and Purpose- We assessed the efficacy and safety of antiplatelet agents after noncardioembolic stroke or transient ischemic attack and examined how these vary according to patients' demographic and clinical ...
Lire la suite >Background and Purpose- We assessed the efficacy and safety of antiplatelet agents after noncardioembolic stroke or transient ischemic attack and examined how these vary according to patients' demographic and clinical characteristics. Methods- We did a network meta-analysis (NMA) of data from 6 randomized trials of the effects of commonly prescribed antiplatelet agents in the long-term (≥3 months) secondary prevention of noncardioembolic stroke or transient ischemic attack. Individual patient data from 43 112 patients were pooled and reanalyzed. Main outcomes were serious vascular events (nonfatal stroke, nonfatal myocardial infarction, or vascular death), major bleeding, and net clinical benefit (serious vascular event or major bleeding). Subgroup analyses were done according to age, sex, ethnicity, hypertension, qualifying diagnosis, type of vessel involved (large versus small vessel disease), and time from qualifying event to randomization. Results- Aspirin/dipyridamole combination (RRNMA-adjNMA-adjNMA-adjNMA-adjNMA-adjLire moins >
Lire la suite >Background and Purpose- We assessed the efficacy and safety of antiplatelet agents after noncardioembolic stroke or transient ischemic attack and examined how these vary according to patients' demographic and clinical characteristics. Methods- We did a network meta-analysis (NMA) of data from 6 randomized trials of the effects of commonly prescribed antiplatelet agents in the long-term (≥3 months) secondary prevention of noncardioembolic stroke or transient ischemic attack. Individual patient data from 43 112 patients were pooled and reanalyzed. Main outcomes were serious vascular events (nonfatal stroke, nonfatal myocardial infarction, or vascular death), major bleeding, and net clinical benefit (serious vascular event or major bleeding). Subgroup analyses were done according to age, sex, ethnicity, hypertension, qualifying diagnosis, type of vessel involved (large versus small vessel disease), and time from qualifying event to randomization. Results- Aspirin/dipyridamole combination (RRNMA-adjNMA-adjNMA-adjNMA-adjNMA-adjLire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T13:37:47Z