Titre :

Insights into the need for permanent pacemaker following implantation of the repositionable lotus valve for transcatheter aortic valve replacement in 250 patients: results from the reprise ii trial with extended cohort

Auteur(s) :

Dumonteil, Nicolas [Auteur]
Meredith, Ian T. [Auteur]
Blackman, Daniel J. [Auteur]
Tchetche, Didier [Auteur]
Hildick-Smith, David [Auteur]
Spence, Mark S. [Auteur]
Walters, Darren L. [Auteur]
Harnek, Jan [Auteur]
Worthley, Stephen G. [Auteur]
Rioufol, Gilles [Auteur]
Lefevre, Thierry [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Van Mieghem, Nicolas M. [Auteur]
Houle, Vicki M. [Auteur]
Allocco, Dominic J. [Auteur]
Dawkins, Keith D. [Auteur]

Titre de la revue :

EuroIntervention . journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Nom court de la revue :

EuroIntervention

Numéro :

13

Pagination :

796-803

Date de publication :

2017-09-01

ISSN :

1774-024X

Mot(s)-clé(s) en anglais :

aortic stenosis
clinical trials
transcatheter aortic valve implantation

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: This analysis aimed to evaluate the incidence and predictors of the need for permanent pacemaker (PPM) implantation following implantation of the repositionable and fully retrievable LOTUS Aortic Valve Replacement ...
Lire la suite >OBJECTIVE: This analysis aimed to evaluate the incidence and predictors of the need for permanent pacemaker (PPM) implantation following implantation of the repositionable and fully retrievable LOTUS Aortic Valve Replacement System. RESULTS: The prospective, single-arm, multicentre REPRISE II study with extended cohort enrolled 250 symptomatic, high surgical risk patients with severe aortic stenosis for transfemoral transcatheter aortic valve implantation (TAVI) with a 23 mm or 27 mm LOTUS valve. Echocardiography, computed tomography, and electrocardiography data were evaluated by independent core labs. Post TAVI, 32.0% (72/225) of pacemaker-naïve patients underwent new PPM implantation at 30 days. Most (59/72, 82%) patients were implanted for third-degree atrioventricular block, and >10% overstretch of the LVOT by area was observed in 59.7% (43/72) of PPM patients. Significant independent predictors of PPM at 30 days included baseline RBBB (odds ratio [OR] 12.7, 95% CI: 4.5, 36.2; p<0.001) and LVOT overstretch >10% (OR 3.4, 95% CI: 1.7, 6.7; p<0.001). There was a trend towards a lower 30-day PPM rate in patients with a shallower (≤5 mm) implant depth (23.9% ≤5 mm vs. 36.9% >5 mm depth from LCS; p=0.06). CONCLUSIONS: Careful attention to valve sizing and implant depth may help to reduce the rate of PPM with the LOTUS valve.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Équipe(s) de recherche :

Troubles cognitifs dégénératifs et vasculaires

Date de dépôt :

2019-11-27T14:28:53Z