Title :

Susceptibility vessel sign on mri predicts better clinical outcome in patients with anterior circulation acute stroke treated with stent retriever as first-line strategy

Author(s) :

Bourcier, Romain [Auteur]
Ben Hassen, Wagih [Auteur]
Soize, Sébastien [Auteur]
Roux, Pascal [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Kyheng, MaÉva [Auteur]
Tisserand, Marie [Auteur]
Rosso, Charlotte [Auteur]
Blanc, Raphael [Auteur]
Piotin, Michel [Auteur]
Derraz, Imad [Auteur]
Boulouis, Gregoire [Auteur]
Oppenheim, Catherine [Auteur]
Desal, Hubert [Auteur]
Bracard, Serge [Auteur]
Lapergue, Bertrand [Auteur]
Naggara, Olivier [Auteur]

Journal title :

Journal of neurointerventional surgery

Abbreviated title :

J Neurointerv Surg

Publication date :

2018-08-28

ISSN :

1759-8486

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

BACKGROUND: Susceptibility vessel sign (SVS) can be a useful MRI biomarker of an occlusion but its relationship with clinical outcomes of acute ischemic stroke (AIS) is yet to be fully elucidated. OBJECTIVE: To investigate ...
Show more >BACKGROUND: Susceptibility vessel sign (SVS) can be a useful MRI biomarker of an occlusion but its relationship with clinical outcomes of acute ischemic stroke (AIS) is yet to be fully elucidated. OBJECTIVE: To investigate SVS in relation to the clinical outcomes after mechanical thrombectomy using a stent retriever (SR) as first-line approach in patients with AIS. METHODS: We included patients with a first-line SR approach for anterior AIS from the the Contact Aspiration vs Stent Retriever for Successful Revascularization (ASTER) and THRombectomie des Artères CErebrales (THRACE) RESULTS: 217 patients were included and SVS was diagnosed in 76.0% of cases (n=165, 95% CI 70.4% to 81.7%). After adjustment for potential confounders, SVS+ was significantly associated with 90-day mRS improvement (adjusted common OR=2.75; 95% CI 1.44 to 5.26) and favorable outcome (adjusted common OR=2.76; 95% CI 1.18 to 6.45). CONCLUSIONS: Based on results for patients of the ASTER and THRACE trials receiving first-line SR treatment, SVS was associated with lower disability at 3 months. Large prospective studies using MRI-based thrombus evaluation are warranted.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2019-11-27T14:29:07Z