Neural correlates of episodic memory in ...
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Neural correlates of episodic memory in the memento cohort
Author(s) :
Epelbaum, Stéphane [Auteur]
Bouteloup, Vincent [Auteur]
Mangin, Jean-François [Auteur]
La Corte, Valentina [Auteur]
Migliaccio, Raffaela [Auteur]
Bertin, Hugo [Auteur]
Habert, Marie-Odile [Auteur]
Fischer, Clara [Auteur]
Azouani, Chabha [Auteur]
Fillon, Ludovic [Auteur]
Chupin, Marie [Auteur]
Vellas, Bruno [Auteur]
Pasquier, Florence [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Dartigues, Jean-François [Auteur]
Blanc, Frederic [Auteur]
Gabelle, Audrey [Auteur]
Ceccaldi, Mathieu [Auteur]
Krolak-Salmon, Pierre [Auteur]
Hugon, Jacques [Auteur]
Hanon, Olivier [Auteur]
Rouaud, Olivier [Auteur]
David, Renaud [Auteur]
Chene, Genevieve [Auteur]
Dubois, Bruno [Auteur]
Dufouil, Carole [Auteur]
Bouteloup, Vincent [Auteur]
Mangin, Jean-François [Auteur]
La Corte, Valentina [Auteur]
Migliaccio, Raffaela [Auteur]
Bertin, Hugo [Auteur]
Habert, Marie-Odile [Auteur]
Fischer, Clara [Auteur]
Azouani, Chabha [Auteur]
Fillon, Ludovic [Auteur]
Chupin, Marie [Auteur]
Vellas, Bruno [Auteur]
Pasquier, Florence [Auteur]

Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Dartigues, Jean-François [Auteur]
Blanc, Frederic [Auteur]
Gabelle, Audrey [Auteur]
Ceccaldi, Mathieu [Auteur]
Krolak-Salmon, Pierre [Auteur]
Hugon, Jacques [Auteur]
Hanon, Olivier [Auteur]
Rouaud, Olivier [Auteur]
David, Renaud [Auteur]
Chene, Genevieve [Auteur]
Dubois, Bruno [Auteur]
Dufouil, Carole [Auteur]
Journal title :
Alzheimer's & dementia (New York, N. Y.)
Abbreviated title :
Alzheimers Dement (N Y)
Volume number :
4
Pages :
224-233
Publication date :
2018-01-01
ISSN :
2352-8737
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic ...
Show more >The free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic memory. We investigated the neural correlates of these three memory processes in a large cohort study. The Memento cohort enrolled 2323 outpatients presenting either with subjective cognitive decline or mild cognitive impairment who underwent cognitive, structural MRI and, for a subset, fluorodeoxyglucose-positron emission tomography evaluations. Encoding was associated with a network including parietal and temporal cortices; storage was mainly associated with entorhinal and parahippocampal regions, bilaterally; retrieval was associated with a widespread network encompassing frontal regions. The neural correlates of episodic memory processes can be assessed in large and standardized cohorts of patients at risk for Alzheimer's disease. Their relation to pathophysiological markers of Alzheimer's disease remains to be studied.Show less >
Show more >The free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic memory. We investigated the neural correlates of these three memory processes in a large cohort study. The Memento cohort enrolled 2323 outpatients presenting either with subjective cognitive decline or mild cognitive impairment who underwent cognitive, structural MRI and, for a subset, fluorodeoxyglucose-positron emission tomography evaluations. Encoding was associated with a network including parietal and temporal cortices; storage was mainly associated with entorhinal and parahippocampal regions, bilaterally; retrieval was associated with a widespread network encompassing frontal regions. The neural correlates of episodic memory processes can be assessed in large and standardized cohorts of patients at risk for Alzheimer's disease. Their relation to pathophysiological markers of Alzheimer's disease remains to be studied.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Research team(s) :
Troubles cognitifs dégénératifs et vasculaires
Submission date :
2019-11-27T14:30:50Z