Predictors, incidence, and outcomes of ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Predictors, incidence, and outcomes of patients undergoing transfemoral transcatheter aortic valve implantation complicated by stroke
Auteur(s) :
Vlastra, Wieneke [Auteur]
Jimenez-Quevedo, Pilar [Auteur]
Tchetche, Didier [Auteur]
Chandrasekhar, Jaya [Auteur]
De Brito, Fabio Sandoli [Auteur]
Barbanti, Marco [Auteur]
Kornowski, Ran [Auteur]
Latib, Azeem [Auteur]
D''''onofrio, Augusto [Auteur]
Ribichini, Flavio [Auteur]
Baan, Jan [Auteur]
Tijssen, Jan G P. [Auteur]
De La Torre Hernandez, Jose M. [Auteur]
Dumonteil, Nicolas [Auteur]
Sarmento-Leite, Rogerio [Auteur]
Sartori, Samantha [Auteur]
Rosato, S. [Auteur]
Tarantini, Giuseppe [Auteur]
Lunardi, Mattia [Auteur]
Orvin, Katia [Auteur]
Pagnesi, Matteo [Auteur]
Hernandez-Antolin, Rosana [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Dangas, George [Auteur]
Mehran, Roxana [Auteur]
Piek, Jan J. [Auteur]
Delewi, Ronak [Auteur]
Jimenez-Quevedo, Pilar [Auteur]
Tchetche, Didier [Auteur]
Chandrasekhar, Jaya [Auteur]
De Brito, Fabio Sandoli [Auteur]
Barbanti, Marco [Auteur]
Kornowski, Ran [Auteur]
Latib, Azeem [Auteur]
D''''onofrio, Augusto [Auteur]
Ribichini, Flavio [Auteur]
Baan, Jan [Auteur]
Tijssen, Jan G P. [Auteur]
De La Torre Hernandez, Jose M. [Auteur]
Dumonteil, Nicolas [Auteur]
Sarmento-Leite, Rogerio [Auteur]
Sartori, Samantha [Auteur]
Rosato, S. [Auteur]
Tarantini, Giuseppe [Auteur]
Lunardi, Mattia [Auteur]
Orvin, Katia [Auteur]
Pagnesi, Matteo [Auteur]
Hernandez-Antolin, Rosana [Auteur]
Modine, Thomas [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Dangas, George [Auteur]
Mehran, Roxana [Auteur]
Piek, Jan J. [Auteur]
Delewi, Ronak [Auteur]
Titre de la revue :
Circulation. Cardiovascular interventions
Nom court de la revue :
Circ Cardiovasc Interv
Numéro :
12
Pagination :
e007546
Date de publication :
2019-03-01
ISSN :
1941-7632
Mot(s)-clé(s) en anglais :
incidence
stroke
transcatheter aortic valve replacement
humans
follow-up studies
stroke
transcatheter aortic valve replacement
humans
follow-up studies
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
BACKGROUND: Stroke remains one of the most devastating complications of transcatheter aortic valve implantation (TAVI). The aim of this study was to identify the incidence, timing, temporal trends, and predictors of stroke ...
Lire la suite >BACKGROUND: Stroke remains one of the most devastating complications of transcatheter aortic valve implantation (TAVI). The aim of this study was to identify the incidence, timing, temporal trends, and predictors of stroke after TAVI and evaluate the outcomes of patients with stroke. RESULTS: The CENTER-Collaboration is an international collaboration consisting of 3 national registries and 7 local registries or prospective clinical trials, selected through a systematic review. Accordingly, a total of 10 982 patients undergoing transfemoral TAVI between 2007 and 2018 were included in the current patient-level pooled analyses. A total of 261 patients (2.4%) experienced stroke during the first month after TAVI. The median time between TAVI and stroke was 1 day (interquartile range, 0-6 days). The stroke rate was comparable in procedures performed in the early years of TAVI (2007-2012) to those in the more recent years of TAVI (2013-2018; both 2.4%; P=1.0). Independent predictors of stroke at 30 days were a history of cerebrovascular events (odds ratio, 2.2; 95% CI, 1.4-3.6; P=0.0012) and a glomerular filtration rate of <30 mL/min per 1.73 m2 CONCLUSIONS: In this large, global, patient-level analysis, the incidence of stroke after transfemoral TAVI was 2.4%. Prior cerebrovascular events and a low glomerular filtration rate independently predicted the occurrence of stroke after TAVI. The occurrence of stroke after TAVI was associated with a strikingly 6-fold increase of 30-day mortality; additionally, there was a 5-fold higher rate of new-onset atrial fibrillation in patients with stroke. BACKGROUND: URL: https://www.clinicaltrials.gov . Unique identifier: NCT03588247.Lire moins >
Lire la suite >BACKGROUND: Stroke remains one of the most devastating complications of transcatheter aortic valve implantation (TAVI). The aim of this study was to identify the incidence, timing, temporal trends, and predictors of stroke after TAVI and evaluate the outcomes of patients with stroke. RESULTS: The CENTER-Collaboration is an international collaboration consisting of 3 national registries and 7 local registries or prospective clinical trials, selected through a systematic review. Accordingly, a total of 10 982 patients undergoing transfemoral TAVI between 2007 and 2018 were included in the current patient-level pooled analyses. A total of 261 patients (2.4%) experienced stroke during the first month after TAVI. The median time between TAVI and stroke was 1 day (interquartile range, 0-6 days). The stroke rate was comparable in procedures performed in the early years of TAVI (2007-2012) to those in the more recent years of TAVI (2013-2018; both 2.4%; P=1.0). Independent predictors of stroke at 30 days were a history of cerebrovascular events (odds ratio, 2.2; 95% CI, 1.4-3.6; P=0.0012) and a glomerular filtration rate of <30 mL/min per 1.73 m2 CONCLUSIONS: In this large, global, patient-level analysis, the incidence of stroke after transfemoral TAVI was 2.4%. Prior cerebrovascular events and a low glomerular filtration rate independently predicted the occurrence of stroke after TAVI. The occurrence of stroke after TAVI was associated with a strikingly 6-fold increase of 30-day mortality; additionally, there was a 5-fold higher rate of new-onset atrial fibrillation in patients with stroke. BACKGROUND: URL: https://www.clinicaltrials.gov . Unique identifier: NCT03588247.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Équipe(s) de recherche :
Troubles cognitifs dégénératifs et vasculaires
Date de dépôt :
2019-11-27T14:31:14Z