Factors of loss to follow-up during ...
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Factors of loss to follow-up during tuberculosis treatment in a low-incidence region
Author(s) :
Tetart, M. [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Meybeck, Agnes [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Assaf, A. [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Valette, Michel [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Choisy, P. [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Blondiaux, Nicolas [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Senneville, Eric [Auteur]
221576|||Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS] (VALID)
Centre Hospitalier Gustave Dron [Tourcoing]
Meybeck, Agnes [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Assaf, A. [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Valette, Michel [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Choisy, P. [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Blondiaux, Nicolas [Auteur]
Centre Hospitalier Gustave Dron [Tourcoing]
Senneville, Eric [Auteur]
221576|||Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS] (VALID)
Journal title :
Médecine et Maladies Infectieuses
Abbreviated title :
Med Mal Infect
Volume number :
50
Pages :
28-35
Publisher :
Elsevier
Publication date :
2019-03-16
ISSN :
1769-6690
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
OBJECTIVE: The proportion of successfully treated tuberculosis (TB) patients remains below the WHO target in France, because of a high proportion of loss to follow-up. We aimed to identify factors associated with loss to ...
Show more >OBJECTIVE: The proportion of successfully treated tuberculosis (TB) patients remains below the WHO target in France, because of a high proportion of loss to follow-up. We aimed to identify factors associated with loss to follow-up in northern France, a low-incidence area. METHODS: Between 1997 and 2017, all consecutive patients diagnosed with TB at the Tourcoing Hospital, except those infected with multidrug-resistant or extensively drug-resistant strains, were included in a retrospective cohort study. A logistic regression analysis was performed to determine factors associated with loss to follow-up. RESULTS: One hundred and ninety patients were included. Previous TB treatment was reported in 32 patients (17%), extrapulmonary TB in 107 (56%), and HIV infection in 44 (23%). The proportion of loss to follow-up was 15%. In multivariate analysis, the risk of loss to follow-up decreased in case of first TB treatment (OR 0.36; 95% CI: 0.14-0.92, P=0.03) and increased in non-HIV-infected patients (OR 7.67; 95% CI: 1.00-59.0, p=0.05). Support for compliance was more frequent in HIV-infected patients (23% vs. 7%, p=0.005). CONCLUSIONS: The proportion of loss to follow-up was high. HIV infection was associated with a lower risk of loss to follow-up, likely to be due to more frequent support for compliance.Show less >
Show more >OBJECTIVE: The proportion of successfully treated tuberculosis (TB) patients remains below the WHO target in France, because of a high proportion of loss to follow-up. We aimed to identify factors associated with loss to follow-up in northern France, a low-incidence area. METHODS: Between 1997 and 2017, all consecutive patients diagnosed with TB at the Tourcoing Hospital, except those infected with multidrug-resistant or extensively drug-resistant strains, were included in a retrospective cohort study. A logistic regression analysis was performed to determine factors associated with loss to follow-up. RESULTS: One hundred and ninety patients were included. Previous TB treatment was reported in 32 patients (17%), extrapulmonary TB in 107 (56%), and HIV infection in 44 (23%). The proportion of loss to follow-up was 15%. In multivariate analysis, the risk of loss to follow-up decreased in case of first TB treatment (OR 0.36; 95% CI: 0.14-0.92, P=0.03) and increased in non-HIV-infected patients (OR 7.67; 95% CI: 1.00-59.0, p=0.05). Support for compliance was more frequent in HIV-infected patients (23% vs. 7%, p=0.005). CONCLUSIONS: The proportion of loss to follow-up was high. HIV infection was associated with a lower risk of loss to follow-up, likely to be due to more frequent support for compliance.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
Université de Lille
Université de Lille
Submission date :
2019-12-09T16:48:17Z
2024-03-27T10:47:13Z
2024-03-27T10:47:13Z