Five-year risk of stroke after tia or minor ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Five-year risk of stroke after tia or minor ischemic stroke
Auteur(s) :
Amarenco, Pierre [Auteur]
Lavallee, Philippa C. [Auteur]
Monteiro Tavares, Linsay [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Albers, Gregory W. [Auteur]
Abboud, Halim [Auteur]
Anticoli, Sabrina [Auteur]
Audebert, Heinrich [Auteur]
Bornstein, Natan M. [Auteur]
Caplan, Louis R. [Auteur]
Correia, Manuel [Auteur]
Donnan, Geoffrey A. [Auteur]
Ferro, Jose M. [Auteur]
Gongora-Rivera, Fernando [Auteur]
Heide, Wolfgang [Auteur]
Hennerici, Michael G. [Auteur]
Kelly, Peter J. [Auteur]
Kral, Michal [Auteur]
Lin, Hsiu-Fen [Auteur]
Molina, Carlos [Auteur]
Park, Jong Moo [Auteur]
Purroy, Francisco [Auteur]
Rothwell, Peter M. [Auteur]
Segura, Tomas [Auteur]
Skoloudik, David [Auteur]
Steg, Philippe Gabriel [Auteur]
Touboul, Pierre-Jean [Auteur]
Uchiyama, Shinichiro [Auteur]
Vicaut, Eric [Auteur]
Wang, Yongjun [Auteur]
Wong, Lawrence K S. [Auteur]
Lavallee, Philippa C. [Auteur]
Monteiro Tavares, Linsay [Auteur]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Albers, Gregory W. [Auteur]
Abboud, Halim [Auteur]
Anticoli, Sabrina [Auteur]
Audebert, Heinrich [Auteur]
Bornstein, Natan M. [Auteur]
Caplan, Louis R. [Auteur]
Correia, Manuel [Auteur]
Donnan, Geoffrey A. [Auteur]
Ferro, Jose M. [Auteur]
Gongora-Rivera, Fernando [Auteur]
Heide, Wolfgang [Auteur]
Hennerici, Michael G. [Auteur]
Kelly, Peter J. [Auteur]
Kral, Michal [Auteur]
Lin, Hsiu-Fen [Auteur]
Molina, Carlos [Auteur]
Park, Jong Moo [Auteur]
Purroy, Francisco [Auteur]
Rothwell, Peter M. [Auteur]
Segura, Tomas [Auteur]
Skoloudik, David [Auteur]
Steg, Philippe Gabriel [Auteur]
Touboul, Pierre-Jean [Auteur]
Uchiyama, Shinichiro [Auteur]
Vicaut, Eric [Auteur]
Wang, Yongjun [Auteur]
Wong, Lawrence K S. [Auteur]
Titre de la revue :
The New England journal of medicine
Nom court de la revue :
N. Engl. J. Med.
Numéro :
378
Pagination :
2182-2190
Date de publication :
2018-06-07
ISSN :
1533-4406
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke and other vascular events is not well known. In this follow-up to a report on 1-year outcomes from a registry of TIA clinics in 21 ...
Lire la suite >After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke and other vascular events is not well known. In this follow-up to a report on 1-year outcomes from a registry of TIA clinics in 21 countries that enrolled 4789 patients with a TIA or minor ischemic stroke from 2009 through 2011, we examined the 5-year risk of stroke and vascular events. We evaluated patients who had had a TIA or minor stroke within 7 days before enrollment in the registry. Among 61 sites that participated in the 1-year outcome study, we selected 42 sites that had follow-up data on more than 50% of their enrolled patients at 5 years. The primary outcome was a composite of stroke, acute coronary syndrome, or death from cardiovascular causes (whichever occurred first), with an emphasis on events that occurred in the second through fifth years. In calculating the cumulative incidence of the primary outcome and secondary outcomes (except death from any cause), we treated death as a competing risk. A total of 3847 patients were included in the 5-year follow-up study; the median percentage of patients with 5-year follow-up data per center was 92.3% (interquartile range, 83.4 to 97.8). The composite primary outcome occurred in 469 patients (estimated cumulative rate, 12.9%; 95% confidence interval [CI], 11.8 to 14.1), with 235 events (50.1%) occurring in the second through fifth years. At 5 years, strokes had occurred in 345 patients (estimated cumulative rate, 9.5%; 95% CI, 8.5 to 10.5), with 149 of these patients (43.2%) having had a stroke during the second through fifth years. Rates of death from any cause, death from cardiovascular causes, intracranial hemorrhage, and major bleeding were 10.6%, 2.7%, 1.1%, and 1.5%, respectively, at 5 years. In multivariable analyses, ipsilateral large-artery atherosclerosis, cardioembolism, and a baseline ABCD2 In a follow-up to a 1-year study involving patients who had a TIA or minor stroke, the rate of cardiovascular events including stroke in a selected cohort was 6.4% in the first year and 6.4% in the second through fifth years. (Funded by AstraZeneca and others.).Lire moins >
Lire la suite >After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke and other vascular events is not well known. In this follow-up to a report on 1-year outcomes from a registry of TIA clinics in 21 countries that enrolled 4789 patients with a TIA or minor ischemic stroke from 2009 through 2011, we examined the 5-year risk of stroke and vascular events. We evaluated patients who had had a TIA or minor stroke within 7 days before enrollment in the registry. Among 61 sites that participated in the 1-year outcome study, we selected 42 sites that had follow-up data on more than 50% of their enrolled patients at 5 years. The primary outcome was a composite of stroke, acute coronary syndrome, or death from cardiovascular causes (whichever occurred first), with an emphasis on events that occurred in the second through fifth years. In calculating the cumulative incidence of the primary outcome and secondary outcomes (except death from any cause), we treated death as a competing risk. A total of 3847 patients were included in the 5-year follow-up study; the median percentage of patients with 5-year follow-up data per center was 92.3% (interquartile range, 83.4 to 97.8). The composite primary outcome occurred in 469 patients (estimated cumulative rate, 12.9%; 95% confidence interval [CI], 11.8 to 14.1), with 235 events (50.1%) occurring in the second through fifth years. At 5 years, strokes had occurred in 345 patients (estimated cumulative rate, 9.5%; 95% CI, 8.5 to 10.5), with 149 of these patients (43.2%) having had a stroke during the second through fifth years. Rates of death from any cause, death from cardiovascular causes, intracranial hemorrhage, and major bleeding were 10.6%, 2.7%, 1.1%, and 1.5%, respectively, at 5 years. In multivariable analyses, ipsilateral large-artery atherosclerosis, cardioembolism, and a baseline ABCD2 In a follow-up to a 1-year study involving patients who had a TIA or minor stroke, the rate of cardiovascular events including stroke in a selected cohort was 6.4% in the first year and 6.4% in the second through fifth years. (Funded by AstraZeneca and others.).Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Université de Lille
Université de Lille
Date de dépôt :
2019-12-09T16:55:55Z
2024-05-23T11:35:47Z
2024-05-23T11:35:47Z