Title :

Impact of iterative reconstruction on the diagnosis of acute pulmonary embolism (pe) on reduced-dose chest ct angiograms

Author(s) :

Pontana, Francois [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Henry, Simon [Auteur]
Duhamel, Alain [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Faivre, Jean-Baptiste [Auteur]
Tacelli, Nunzia [Auteur]
Pagniez, Julien [Auteur]
Remy, Jacques [Auteur]
Remy, Martine [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]

Journal title :

European radiology

Abbreviated title :

Eur. Radiol.

Volume number :

25

Pages :

1182-1189

Publication date :

2015-04-01

ISSN :

0938-7994

English keyword(s) :

Chest
Radiation dose
CT
Iterative reconstruction
Pulmonary embolism

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

OBJECTIVE: To evaluate the impact of iterative reconstruction on the detectability of clots. METHODS: Fifty-three patients were enrolled in a study comparing reduced-dose and full-dose images, available from the same ...
Show more >OBJECTIVE: To evaluate the impact of iterative reconstruction on the detectability of clots. METHODS: Fifty-three patients were enrolled in a study comparing reduced-dose and full-dose images, available from the same dual-source data set. From each acquisition, three series of images were generated: (1) full-dose images (from both tubes), reconstructed with filtered back projection (FBP) (group 1; standard of reference), (2) reduced-dose images (from tube A only; 60 % dose reduction) reconstructed with FBP (group 2) and iterative reconstruction (SAFIRE) (group 3). RESULTS: In group 1 (mean DLP: 264.6 mGy.cm), (1) PE was diagnosed in 8 patients (15 %) with 82 clots in the central (n = 5), segmental (n = 39) and subsegmental (n = 38) arteries and (2) mean level of noise was 30.56 ± 5.07. In group 2 (mean DLP: 105.8 mGy.cm), a significant increase in noise (44.56 ± 6.24; p < 0.0001) (1) hampered detection of PE in one patient and (2) altered detection of peripheral clots (12 false-negative and 2 false-positive results). In group 3, image noise was not significantly different from that in group 1 (p = 0.1525; effect size: 0.2683), with a similar detection of PE compared to group 1 (p = 1). CONCLUSIONS: Reconstruction of reduced-dose images (60 % dose reduction) with SAFIRE provided image quality and diagnostic value comparable to those of full-dose FBP images. CONCLUSIONS: • Iterative reconstruction does not alter the detection of endoluminal clots. • Iterative reconstruction allows dose reduction in the context of acute PE. • Iterative reconstruction allows radiologists to approach the prospects of submilliSievert CT.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Institut Pasteur de Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (EGID) - U1011

Submission date :

2019-12-09T18:15:16Z