Title :

Impact of ct perfusion imaging on the assessment of peripheral chronic pulmonary thromboembolism: clinical experience in 62 patients

Author(s) :

Le Faivre, Julien [Auteur]
Duhamel, Alain [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Khung, Suonita [Auteur]
Faivre, Jean-Baptiste [Auteur]
Lamblin, Nicolas [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Remy, Jacques [Auteur]
Remy, Martine [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]

Journal title :

European radiology

Abbreviated title :

Eur. Radiol.

Volume number :

26

Pages :

4011-4020

Publication date :

2016-11-01

ISSN :

0938-7994

English keyword(s) :

CT angiography
Chronic thromboembolism
Pulmonary hypertension
Dual-energy lung perfusion imaging
Dual-energy CT

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

OBJECTIVE: To evaluate the impact of CT perfusion imaging on the detection of peripheral chronic pulmonary embolisms (CPE). METHODS: 62 patients underwent a dual-energy chest CT angiographic examination with (a) reconstruction ...
Show more >OBJECTIVE: To evaluate the impact of CT perfusion imaging on the detection of peripheral chronic pulmonary embolisms (CPE). METHODS: 62 patients underwent a dual-energy chest CT angiographic examination with (a) reconstruction of diagnostic and perfusion images; (b) enabling depiction of vascular features of peripheral CPE on diagnostic images and perfusion defects (20 segments/patient; total: 1240 segments examined). The interpretation of diagnostic images was of two types: (a) standard (i.e., based on cross-sectional images alone) or (b) detailed (i.e., based on cross-sectional images and MIPs). RESULTS: The segment-based analysis showed (a) 1179 segments analyzable on both imaging modalities and 61 segments rated as nonanalyzable on perfusion images; (b) the percentage of diseased segments was increased by 7.2 % when perfusion imaging was compared to the detailed reading of diagnostic images, and by 26.6 % when compared to the standard reading of images. At a patient level, the extent of peripheral CPE was higher on perfusion imaging, with a greater impact when compared to the standard reading of diagnostic images (number of patients with a greater number of diseased segments: n = 45; 72.6 % of the study population). CONCLUSIONS: Perfusion imaging allows recognition of a greater extent of peripheral CPE compared to diagnostic imaging. CONCLUSIONS: • Dual-energy computed tomography generates standard diagnostic imaging and lung perfusion analysis. • Depiction of CPE on central arteries relies on standard diagnostic imaging. • Detection of peripheral CPE is improved by perfusion imaging.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Institut Pasteur de Lille
Université de Lille

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2019-12-09T18:15:25Z