Title :

Twenty-four-hour blood pressure monitoring to predict and assess impact of renal denervation the denerhtn study (renal denervation for hypertension)

Author(s) :

Gosse, Philippe [Auteur]
Cremer, Antoine [Auteur]
Pereira, Helena [Auteur]
Bobrie, Guillaume [Auteur]
Chatellier, Gilles [Auteur]
Chamontin, Bernard [Auteur]
Courand, Pierre-Yves [Auteur]
Delsart, Pascal [Auteur]
Denolle, Thierry [Auteur]
Dourmap-Collas, Caroline [Auteur]
Ferrari, Emile [Auteur]
Girerd, Xavier [Auteur]
Halimi, Jean-Michel [Auteur]
Herpin, Daniel [Auteur]
Lantelme, Pierre [Auteur]
Monge, Matthieu [Auteur]
Mounier Vehier, Claire [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Mourad, Jean-Jacques [Auteur]
Ormezzano, Olivier [Auteur]
Ribstein, Jean [Auteur]
Rossignol, Patrick [Auteur]
Sapoval, Marc [Auteur]
Vaisse, Bernard [Auteur]
Zannad, Faiez [Auteur]
Azizi, Michel [Auteur]

Journal title :

Hypertension (Dallas, Tex. . 1979)

Abbreviated title :

Hypertension

Volume number :

69

Pages :

494-+

Publication date :

2017-03-01

ISSN :

0194-911X

English keyword(s) :

resistant hypertension
blood pressure variability
ambulatory blood pressure monitoring
renal denervation
smoothness index

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The DENERHTN trial (Renal Denervation for Hypertension) confirmed the blood pressure (BP) lowering efficacy of renal denervation added to a standardized stepped-care antihypertensive treatment for resistant hypertension ...
Show more >The DENERHTN trial (Renal Denervation for Hypertension) confirmed the blood pressure (BP) lowering efficacy of renal denervation added to a standardized stepped-care antihypertensive treatment for resistant hypertension at 6 months. We report here the effect of denervation on 24-hour BP and its variability and look for parameters that predicted the BP response. Patients with resistant hypertension were randomly assigned to denervation plus stepped-care treatment or treatment alone (control). Average and standard deviation of 24-hour, daytime, and nighttime BP and the smoothness index were calculated on recordings performed at randomization and 6 months. Responders were defined as a 6-month 24-hour systolic BP reduction ≥20 mm Hg. Analyses were performed on the per-protocol population. The significantly greater BP reduction in the denervation group was associated with a higher smoothness index (PP URL: https://www.clinicaltrials.gov. Unique identifier: NCT01570777.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2019-12-09T18:15:59Z