Titre :

Catheter ablation reduces ventricular tachycardia burden in patients with arrhythmogenic right ventricular cardiomyopathy: insights from a north-western french multicentre registry

Auteur(s) :

Souissi, Zouheir [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Boulé, Stéphane [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hermida, Jean-Sylvain [Auteur]
CHU Amiens-Picardie
Doucy, Alexandre [Auteur]
CHU Amiens-Picardie
Mabo, Philippe [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Pavin, Dominique [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Anselme, Frederic [Auteur]
CHU Rouen
Auquier, Nathanael [Auteur]
CHU Rouen
Ninni, Sandro [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Coisne, Augustin [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Brigadeau, François [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Deken-Delannoy, Valérie [Auteur]
Santé Publique : épidémiologie et qualité des soins [EA 2694]
Klug, Didier [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Lacroix, Dominique [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]

Titre de la revue :

Europace . European pacing, arrhythmias, and cardiac electrophysiology . journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Nom court de la revue :

Europace

Numéro :

20

Pagination :

362-369

Éditeur :

Oxford Academic

Date de publication :

2018-02-01

ISSN :

1099-5129

Mot(s)-clé(s) en anglais :

Arrhythmogenic right ventricular cardiomyopathy
Ventricular tachycardia
Catheter ablation

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Studies assessing radiofrequency ablation (RFA) of ventricular tachycardia (VT) in arrhythmogenic right ventricular cardiomyopathy (ARVC) report VT recurrences, but have not evaluated the impact of RFA on relevant clinical ...
Lire la suite >Studies assessing radiofrequency ablation (RFA) of ventricular tachycardia (VT) in arrhythmogenic right ventricular cardiomyopathy (ARVC) report VT recurrences, but have not evaluated the impact of RFA on relevant clinical events during follow-up. We aimed to investigate relevant RFA outcomes in a multicentric registry. This study included 49 patients with ARVC (46 with definite diagnosis, 3 with borderline diagnosis according to revised Task Force Criteria) who underwent 92 RFA procedures (83 endocardial, 9 combined endo-epicardial) between 1999-2015. Ventricular tachycardia recurrences and VT burden were assessed after each procedure or after the last RFA. Over a mean follow-up of 64 ± 51 months, VT-free survival was 37% at 1 year, 19% at 5 years, and 14% at 10 years. Ventricular tachycardia burden was significantly reduced after one procedure (23 vs. 11 VT episodes/year, P < 0.01) and after the last RFA (14 vs. 2 VT episodes/year, P < 0.01). Over a mean follow-up of 49 ± 52 months, clinical response after the last RFA (freedom from sudden cardiac death, VT requiring hospitalization, or heart transplantation) was 86% at 1 year, 69% at 5 years, and 60% at 10 years. Clinical response was associated with right ventricular dysfunction (RVD) and low numbers of mappable VT before the first RFA. RFA was predominantly targeted at the endocardial surface. Ventricular tachycardia recurrences were common, but few ARVC patients experienced major clinical events during follow-up. Further studies should investigate the benefit of extensive substrate ablation combined with endo-epicardial strategies.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2019-12-09T18:17:49Z
2024-04-03T08:26:30Z