Titre :

Reappraisal of eligibility criteria in cancer clinical trials

Auteur(s) :

Penel, Nicolas [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Lebellec, Loic [Auteur]
Université de Lille
Vanseymortier, Marie [Auteur]
Centre Régional de Lutte contre le Cancer Oscar Lambret [Lille] [UNICANCER/Lille]

Titre de la revue :

Current opinion in oncology

Nom court de la revue :

Curr Opin Oncol

Numéro :

30

Pagination :

352-357

Éditeur :

Wolters Kluwer

Date de publication :

2018-07-16

ISSN :

1531-703X

Mot(s)-clé(s) en anglais :

cancer clinical trials
generalizability
phase trials
eligibility criteria
participant protection

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

We aimed to summarize the recent reflections and collaborative initiatives pertaining to the definition of more appropriate eligibility criteria in cancer clinical trials. There is an intrinsic tension between two opposite ...
Lire la suite >We aimed to summarize the recent reflections and collaborative initiatives pertaining to the definition of more appropriate eligibility criteria in cancer clinical trials. There is an intrinsic tension between two opposite purposes when it comes to defining eligibility criteria: on the one hand, participants must be protected, and on the other, the study population must be defined as accurately as possible. However, stringent eligibility criteria jeopardize the feasibility of trials, and, consequently, the generalizability of trial results. Therefore, interdisciplinary working groups under the auspices of the American Society of Clinical Oncology and Friends of Cancer Research propose to adapt/relax some of the classical eligibility criteria. In-depth reflection of the existing eligibility criteria, and implementation of recent recommendations are needed.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2019-12-09T18:19:01Z
2024-03-06T11:11:51Z