Titre :

Prevalence of asymptomatic coronary disease in fibrosing idiopathic interstitial pneumonias

Auteur(s) :

Cassagnes, Lucie [Auteur]
Gaillard, Vianney [Auteur]
Monge, Emmanuel [Auteur]
Faivre, Jean-Baptiste [Auteur]
Delhaye, Cedric [Auteur]
Molinari, Francesco [Auteur]
Petyt, Gregory [Auteur]
Hossein-Foucher, Claude [Auteur]
Wallaert, Benoit [Auteur]
Duhamel, Alain [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Remy, Jacques [Auteur]
Remy, Martine [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Titre de la revue :

European journal of radiology

Nom court de la revue :

Eur. J. Radiol.

Numéro :

84

Pagination :

163-171

Date de publication :

2015-01-01

ISSN :

0720-048X

Mot(s)-clé(s) en anglais :

Chest CT
Atherosclerosis
Interstitial lung disease
Coronary arteries
Lung diseases

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

BACKGROUND: Because of growing body of interest on the association between fibrosing idiopathic interstitial pneumonias (f-IIP) and ischaemic heart disease, we initiated this prospective study to evaluate the prevalence ...
Lire la suite >BACKGROUND: Because of growing body of interest on the association between fibrosing idiopathic interstitial pneumonias (f-IIP) and ischaemic heart disease, we initiated this prospective study to evaluate the prevalence of asymptomatic coronary artery disease (CAD) in patients with f-IIP. METHODS: Forty-two patients with f-IIP underwent noninvasive screening for CAD that included (a) a chest CT examination enabling calculation of the coronary artery calcium (CAC) score, then depiction of coronary artery stenosis; and (b) stress myocardial perfusion scintigraphy (MPS). Patients with significant coronary abnormalities, defined by a CAC score >400 or coronary artery stenosis >50% at CT and/or perfusion defect >5% at MPS, were referred to the cardiologist. Coronary angiography was indicated in presence of a perfusion defect >10% at MPS or significant left main or proximal left anterior descending stenosis whatever MPS findings. RESULTS: Combining CT and MPS, significant abnormalities were detected in 32/42 patients (76%). The cardiologist: (a) did not consider further investigation in 21 patients (CT abnormalities but no ischaemia at MPS: 12/21; false-positive findings at MPS: 3/21; poor respiratory condition: 6/21); (b) proceeded to coronary angiography in 11 patients which confirmed significant stenoses in 5 patients (5/42; 12%). In the worst-case-scenario (i.e., inclusion of 6 patients with significant coronary artery abnormalities who were not investigated due to poor respiratory condition), the prevalence of CAD reached 26% (11/42). CONCLUSIONS: In the studied population of patients with f-IIP, asymptomatic CAD ranged between 12% and 26%.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2020-02-11T09:07:27Z