Ionic current inversion in pressure-driven ...
Document type :
Article dans une revue scientifique
PMID :
Permalink :
Title :
Ionic current inversion in pressure-driven polymer translocation through nanopores
Author(s) :
Buyukdagli, Sahin [Auteur]
Universite Bilkent [Ankara]
Blossey, Ralf [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF]
Ala-Nissila, T. [Auteur]
Department of Physics [Providence]
Universite Bilkent [Ankara]
Blossey, Ralf [Auteur]

Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF]
Ala-Nissila, T. [Auteur]
Department of Physics [Providence]
Journal title :
Physical Review Letters
Abbreviated title :
Phys. Rev. Lett.
Volume number :
114
Pages :
088303
Publication date :
2015-02-27
ISSN :
1079-7114
English keyword(s) :
Models, Chemical
DNA
Electrolytes
Hydrodynamics
Cations
Static Electricity
Nanopores
DNA
Electrolytes
Hydrodynamics
Cations
Static Electricity
Nanopores
HAL domain(s) :
Chimie/Chimie théorique et/ou physique
English abstract : [en]
We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field ...
Show more >We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics. In the presence of multivalent counterions, electrostatic many-body effects result in the reversal of the DNA charge. The attraction of anions to the charge-inverted DNA molecule reverses the sign of the ionic current through the pore. Our theory allows for a comprehensive understanding of the complex features of the resulting streaming currents. The underlying mechanism is an efficient way to detect DNA charge reversal in pressure-driven translocation experiments with multivalent cations.Show less >
Show more >We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics. In the presence of multivalent counterions, electrostatic many-body effects result in the reversal of the DNA charge. The attraction of anions to the charge-inverted DNA molecule reverses the sign of the ionic current through the pore. Our theory allows for a comprehensive understanding of the complex features of the resulting streaming currents. The underlying mechanism is an efficient way to detect DNA charge reversal in pressure-driven translocation experiments with multivalent cations.Show less >
Language :
Anglais
Audience :
Non spécifiée
Administrative institution(s) :
CNRS
Université de Lille
Université de Lille
Research team(s) :
Computational Molecular Systems Biology
Submission date :
2020-02-12T15:11:17Z
2021-04-21T07:21:05Z
2021-04-21T07:21:05Z