Biological based Biosensor’s Inception

Spriet, Corentin; Kasprowicz, Angelina; Bodart, Jean-Francois

Document type :

Article dans une revue scientifique

DOI :

10.15226/2575-6303/1/1/00103

Permalink :

http://hdl.handle.net/20.500.12210/18513

Title :

Biological based Biosensor’s Inception

Author(s) :

Spriet, Corentin [Auteur]

Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Kasprowicz, Angelina [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Bodart, Jean-Francois [Auteur]

Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]

Journal title :

Journal of Biosensors, Biomarkers and Diagnostics

Volume number :

Pages :

1-2

Publication date :

2016-08-05

HAL domain(s) :

Chimie/Chimie théorique et/ou physique

English abstract : [en]

As an incipit, one has to define the term biosensor. The term has been enclosing several views and concepts, which we will not review here. Nevertheless, biological based biosensors can be common only defined as biological ...
Show more >As an incipit, one has to define the term biosensor. The term has been enclosing several views and concepts, which we will not review here. Nevertheless, biological based biosensors can be common only defined as biological items, whose properties modifications upon environmental modifications can be measured. Herein this opinion article we will refer only to biosensors as the biological based ones, which cover [1] molecules : among the best characterized biosensors are the FRET (Förster Resonance Energy Transfer)-based, genetically encoded Kinase Activity Reporter (KAR) [1,2], (2) cells : CBB (Cells Based Biosensors; [3] and (3) organisms, like Xenopus embryos, whose development is sensitive to external factors (FETAX), Frog Embryo Teratogenesis Assay Xenopus [4] (Figure 1A). The untangling of complex signalling network is imperative both for understanding cells and organisms physiological and pathological contexts, and for isolating the ideal property modifications to measure that will reflect, for example, the deregulation of these networks. These modifications are the one seeked for biosensors design or choice. Then, biosensors become mandatory for deciphering and characterizing molecular signatures associated with pathologies. The latter aspect is naturally tightly linked to prognosis and diagnosis.Show less >

Language :

Anglais

Audience :

Non spécifiée

Administrative institution(s) :

CNRS
Université de Lille

Collections :

Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576

Research team(s) :

Régulation des signaux de division

Submission date :

2020-02-12T15:44:33Z
2021-03-05T08:08:10Z
2021-03-05T08:09:21Z
2021-03-05T08:10:50Z

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Version	Link	Modification date
4	20.500.12210/18513*	2021-03-05T08:10:10Z
1	20.500.12210/18513.1	2020-02-12T15:44:33Z

Biological based Biosensor’s Inception

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