Title :

Self-Cleaning Interfaces of Polydimethylsiloxane Grafted with pH-Responsive Zwitterionic Copolymers

Author(s) :

de Vera, Jacqueline S. [Auteur]
Chung Yuan Christian University
Venault, Antoine [Auteur]
Chung Yuan Christian University
Chou, Ying-Nien [Auteur]
Chung Yuan Christian University
Tayo, Lemmuel [Auteur]
Chiang, Heng-Chieh [Auteur]
Aimar, Pierre [Auteur]
Laboratoire de Génie Chimique [LGC]
Chang, Yung [Auteur]
Chung Yuan Christian University

Journal title :

LANGMUIR

Pages :

1357-1368

Publisher :

American Chemical Society

Publication date :

2019

ISSN :

0743-7463

English keyword(s) :

Polydimethylsiloxane
Zwitterionic Interfaces

HAL domain(s) :

Chimie/Polymères

English abstract : [en]

Self-cleaning surfaces allow the reversible attachment and detachment of microorganisms which show great promise in regards to their reusability as smart biomaterials. However, a widely used biomaterial such as ...
Show more >Self-cleaning surfaces allow the reversible attachment and detachment of microorganisms which show great promise in regards to their reusability as smart biomaterials. However, a widely used biomaterial such as polydimethylsiloxane (PDMS) suffers from high biofouling activity and hydrophobic recovery that results in decreased efficiency and stability. A current challenge is to modify and fabricate self-cleaning PDMS surfaces by incorporating antifouling and pH-sensitive properties. To address this, we synthesized a zwitterionic and pH-sensitive random poly(glycidyl methacrylate-co-sulfobetaine methacrylate-co-2-(dimethylamino)ethyl methacrylate) polymer, poly(GMA-co-SBMA-co-DMAEMA). In this work, chemical modification of PDMS was done by grafting onto poly(GMA-co-SBMA-co-DMAEMA) after surface activation via UV and ozone for 90 min to ensure the formation of covalent bonds necessary for stable grafting. The PDMS grafted with G20-S40-D40 exhibit antifouling and pH-sensitive properties by mitigating fibrinogen adsorption, blood cell adhesion, and releasing 98% adhered E. coli bacteria after immersion at basic pH. The grafting of poly(GMA-co-SBMA-co-DMAEMA) presented in this work shows attractive potential for biomedical and industrial applications as a simple, smart, and effective method for the modification of PDMS interfacesShow less >

Language :

Anglais

Popular science :

Non

ANR Project :

Membrane à architecture controlée à la nanoéchelle pour la séparation de protéine

Collections :

• Centre de Recherche en Informatique, Signal et Automatique de Lille (CRIStAL) - UMR 9189

Source :

Harvested from HAL