Self-Cleaning Interfaces of Polydimethylsiloxane ...
Document type :
Compte-rendu et recension critique d'ouvrage
Title :
Self-Cleaning Interfaces of Polydimethylsiloxane Grafted with pH-Responsive Zwitterionic Copolymers
Author(s) :
de Vera, Jacqueline S. [Auteur]
Chung Yuan Christian University
Venault, Antoine [Auteur]
Chung Yuan Christian University
Chou, Ying-Nien [Auteur]
Chung Yuan Christian University
Tayo, Lemmuel [Auteur]
Chiang, Heng-Chieh [Auteur]
Aimar, Pierre [Auteur]
Laboratoire de Génie Chimique [LGC]
Chang, Yung [Auteur]
Chung Yuan Christian University
Chung Yuan Christian University
Venault, Antoine [Auteur]
Chung Yuan Christian University
Chou, Ying-Nien [Auteur]
Chung Yuan Christian University
Tayo, Lemmuel [Auteur]
Chiang, Heng-Chieh [Auteur]
Aimar, Pierre [Auteur]
Laboratoire de Génie Chimique [LGC]
Chang, Yung [Auteur]
Chung Yuan Christian University
Journal title :
LANGMUIR
Pages :
1357-1368
Publisher :
American Chemical Society
Publication date :
2019
ISSN :
0743-7463
English keyword(s) :
Polydimethylsiloxane
Zwitterionic Interfaces
Zwitterionic Interfaces
HAL domain(s) :
Chimie/Polymères
English abstract : [en]
Self-cleaning surfaces allow the reversible attachment and detachment of microorganisms which show great promise in regards to their reusability as smart biomaterials. However, a widely used biomaterial such as ...
Show more >Self-cleaning surfaces allow the reversible attachment and detachment of microorganisms which show great promise in regards to their reusability as smart biomaterials. However, a widely used biomaterial such as polydimethylsiloxane (PDMS) suffers from high biofouling activity and hydrophobic recovery that results in decreased efficiency and stability. A current challenge is to modify and fabricate self-cleaning PDMS surfaces by incorporating antifouling and pH-sensitive properties. To address this, we synthesized a zwitterionic and pH-sensitive random poly(glycidyl methacrylate-co-sulfobetaine methacrylate-co-2-(dimethylamino)ethyl methacrylate) polymer, poly(GMA-co-SBMA-co-DMAEMA). In this work, chemical modification of PDMS was done by grafting onto poly(GMA-co-SBMA-co-DMAEMA) after surface activation via UV and ozone for 90 min to ensure the formation of covalent bonds necessary for stable grafting. The PDMS grafted with G20-S40-D40 exhibit antifouling and pH-sensitive properties by mitigating fibrinogen adsorption, blood cell adhesion, and releasing 98% adhered E. coli bacteria after immersion at basic pH. The grafting of poly(GMA-co-SBMA-co-DMAEMA) presented in this work shows attractive potential for biomedical and industrial applications as a simple, smart, and effective method for the modification of PDMS interfacesShow less >
Show more >Self-cleaning surfaces allow the reversible attachment and detachment of microorganisms which show great promise in regards to their reusability as smart biomaterials. However, a widely used biomaterial such as polydimethylsiloxane (PDMS) suffers from high biofouling activity and hydrophobic recovery that results in decreased efficiency and stability. A current challenge is to modify and fabricate self-cleaning PDMS surfaces by incorporating antifouling and pH-sensitive properties. To address this, we synthesized a zwitterionic and pH-sensitive random poly(glycidyl methacrylate-co-sulfobetaine methacrylate-co-2-(dimethylamino)ethyl methacrylate) polymer, poly(GMA-co-SBMA-co-DMAEMA). In this work, chemical modification of PDMS was done by grafting onto poly(GMA-co-SBMA-co-DMAEMA) after surface activation via UV and ozone for 90 min to ensure the formation of covalent bonds necessary for stable grafting. The PDMS grafted with G20-S40-D40 exhibit antifouling and pH-sensitive properties by mitigating fibrinogen adsorption, blood cell adhesion, and releasing 98% adhered E. coli bacteria after immersion at basic pH. The grafting of poly(GMA-co-SBMA-co-DMAEMA) presented in this work shows attractive potential for biomedical and industrial applications as a simple, smart, and effective method for the modification of PDMS interfacesShow less >
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Anglais
Popular science :
Non
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