Impaired multisensory integration and ...
Document type :
Article dans une revue scientifique
Permalink :
Title :
Impaired multisensory integration and disruption of spatial references in anorexia nervosa
Author(s) :
Carey, Aurélie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Luyat, Marion [Auteur]
Psychologie : Interactions, Temps, Émotions, Cognition (PSITEC) - ULR 4072
Cottencin, Olivier [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Thomas, Pierre [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Guardia, Dewi [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Luyat, Marion [Auteur]

Psychologie : Interactions, Temps, Émotions, Cognition (PSITEC) - ULR 4072
Cottencin, Olivier [Auteur]

Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Thomas, Pierre [Auteur]

Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Guardia, Dewi [Auteur]

Lille Neurosciences & Cognition (LilNCog) - U 1172
Journal title :
European Psychiatry
Volume number :
28
Pages :
1
Publication date :
2013-07
ISSN :
09249338
HAL domain(s) :
Sciences cognitives
English abstract : [en]
In anorexia nervosa (AN), body distortions have been associated with right parietal cortex (PC) dysfunction. The PC is the anatomical substrate for a supramodal reference framework involved in spatial orientation constancy. ...
Show more >In anorexia nervosa (AN), body distortions have been associated with right parietal cortex (PC) dysfunction. The PC is the anatomical substrate for a supramodal reference framework involved in spatial orientation constancy. Our aim was to evaluate spatial orientation constancy and the perception of body posture in AN patients. In this case control study, the population consisted of 25 AN patients and 25 healthy controls. We investigated the effect of passive lateral body inclination on the visual and tactile subjective vertical (SV) and body Z-axis perception in each group. Subjects performed visual- and tactile- spatial judgments of axis orientations in an upright position and tilted 90° ckwise or counterclockwise. We observed a significant deviation of the tactile and visual SV towards the body (an A-effect) under tilted conditions, suggesting a multisensory spatial orientation deficit. Significant deviation of the Z-axis in the direction of the tilt was also observed in the AN group. The greatest A-effect in AN patients could reflect reduced interoceptive awareness and thus inadequate consideration of gravitational inflow. Furthermore, marked body weight loss could decrease the somatosensory inputs involved for spatial orientation. Our study results strengthen the role of PC in AN. These suggest that spatial references are impaired in AN, which could be due to disrupted multisensory integration in the PC such as visual, tactile, vestibular and somatosensory information.Show less >
Show more >In anorexia nervosa (AN), body distortions have been associated with right parietal cortex (PC) dysfunction. The PC is the anatomical substrate for a supramodal reference framework involved in spatial orientation constancy. Our aim was to evaluate spatial orientation constancy and the perception of body posture in AN patients. In this case control study, the population consisted of 25 AN patients and 25 healthy controls. We investigated the effect of passive lateral body inclination on the visual and tactile subjective vertical (SV) and body Z-axis perception in each group. Subjects performed visual- and tactile- spatial judgments of axis orientations in an upright position and tilted 90° ckwise or counterclockwise. We observed a significant deviation of the tactile and visual SV towards the body (an A-effect) under tilted conditions, suggesting a multisensory spatial orientation deficit. Significant deviation of the Z-axis in the direction of the tilt was also observed in the AN group. The greatest A-effect in AN patients could reflect reduced interoceptive awareness and thus inadequate consideration of gravitational inflow. Furthermore, marked body weight loss could decrease the somatosensory inputs involved for spatial orientation. Our study results strengthen the role of PC in AN. These suggest that spatial references are impaired in AN, which could be due to disrupted multisensory integration in the PC such as visual, tactile, vestibular and somatosensory information.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Université de Lille
CNRS
Université de Lille
Collections :
Research team(s) :
Neuropsychologie & Audition
Submission date :
2020-09-14T10:32:21Z
2021-09-15T09:53:04Z
2021-09-15T09:53:04Z