Titre :

LABiocin database: A new database designed specifically for Lactic Acid Bacteria bacteriocins

Auteur(s) :

Kassaa, Imad AL [Auteur]

Rafei, Rayane [Auteur]

Moukhtar, Mirna [Auteur]

Zaylaa, Mazen [Auteur]

Gharsallaoui, Adem [Auteur]
Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires [BIODYMIA]
Asehraou, Abdeslam [Auteur]
Université Mohammed Premier [Oujda] = Université Mohammed Ier
Omari, Khaled El [Auteur]

Shahin, Ahmad [Auteur]

Hamze, Monzer [Auteur]

Chihib, Nour-Eddine [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Unité Matériaux et Transformations (UMET) - UMR 8207

Titre de la revue :

International Journal of Antimicrobial Agents

Nom court de la revue :

International Journal of Antimicrobial Agents

Numéro :

54

Pagination :

771-779

Éditeur :

Elsevier BV

Date de publication :

2019-12

ISSN :

0924-8579

Mot(s)-clé(s) en anglais :

Bacteriocins
Databases
LAB
Antimicrobial peptides
LABiocin

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Ingénierie des aliments

Résumé en anglais : [en]

Bacteriocins from lactic acid bacteria (LAB) are successfully applied as natural alternatives to food preservation and to antibiotics; however, information on these antimicrobial peptides (AMPs) is scattered through the ...
Lire la suite >Bacteriocins from lactic acid bacteria (LAB) are successfully applied as natural alternatives to food preservation and to antibiotics; however, information on these antimicrobial peptides (AMPs) is scattered through the literature and databases. Therefore, we developed the LABiocin database, a specialized database on LAB bacteriocins. The database was stored and compiled using MySQL with NetBeans IDE as the platform. Important data are compiled, including bacteriocin name, class, amino acids and nucleic acid sequences, if available. Target microorganisms, origin, status of the producing strains and their culture conditions and extraction and purification methods are also included in this new database. A phylogenetic tree for the mature peptide bacteriocin sequences has also been created. LABiocin is an interactive database with a user-friendly interface that integrates several tools and services and comprises up to 517 LAB bacteriocins. Besides data searching tools, a BLAST tool was integrated into the database to enable the user to perform a homology search against mature peptide sequences. Users can be linked to other databases that contain additional information, particularly about predicted bacteriocin structure and mechanisms of action. The LABiocin database enables comprehensive functional analysis of this special group of AMPs. This would be useful in food preservation and food safety applications and would also have substantial implications for development of new drugs for medical use. LABiocin database is available at labiocin.net.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
CNRS
INRA
ENSCL

Collections :

• Unité Matériaux et Transformations (UMET) - UMR 8207

Équipe(s) de recherche :

Processus aux Interfaces et Hygiène des Matériaux (PIHM)

Date de dépôt :

2020-12-14T10:38:54Z