Titre :

Intermediate degrees of synergistic pleiotropy drive adaptive evolution in ecological time

Auteur(s) :

Frachon, Léa [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Libourel, Cyril [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Villoutreix, Romain [Auteur]
Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)]
Carrere, Sébastien [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Glorieux, Cédric [Auteur]
Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)]
Huard-Chauveau, Carine [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Navascués, Miguel [Auteur]
Institut de Biologie Computationnelle [IBC]
Centre de Biologie pour la Gestion des Populations [UMR CBGP]
Gay, Laurène [Auteur]
Amélioration génétique et adaptation des plantes méditerranéennes et tropicales [UMR AGAP]
Vitalis, Renaud [Auteur]
Institut de Biologie Computationnelle [IBC]
Centre de Biologie pour la Gestion des Populations [UMR CBGP]
Baron, Etienne [Auteur]
Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)]
Amsellem, Laurent [Auteur]
Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)]
Bouchez, Olivier [Auteur]
Génétique Physiologie et Systèmes d'Elevage [GenPhySE]
Génome et Transcriptome - Plateforme Génomique [GeT-PlaGe]
Vidal, Marie [Auteur]
Département Génétique Animale [DEPT GA]
Génome et Transcriptome - Plateforme Génomique [GeT-PlaGe]
Le Corre, Valérie [Auteur]
Agroécologie [Dijon]
Roby, Dominique [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Bergelson, Joy [Auteur]
Department of Ecology and Evolution [Chicago]
Roux, Fabrice [Auteur]
Laboratoire des interactions plantes micro-organismes [LIPM]
Évolution, Écologie et Paléontologie (Evo-Eco-Paleo) - UMR 8198 [Evo-Eco-Paléo (EEP)]

Titre de la revue :

Nature Ecology & Evolution

Pagination :

1551-1561

Éditeur :

Nature

Date de publication :

2017-10

ISSN :

2397-334X

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Génétique/Génétique des populations [q-bio.PE]

Résumé en anglais : [en]

Rapid phenotypic evolution of quantitative traits can occur within years, but its underlying genetic architecture remains uncharacterized. Here we test the theoretical prediction that genes with intermediate pleiotropy ...
Lire la suite >Rapid phenotypic evolution of quantitative traits can occur within years, but its underlying genetic architecture remains uncharacterized. Here we test the theoretical prediction that genes with intermediate pleiotropy drive adaptive evolution in nature. Through a resurrection experiment, we grew Arabidopsis thaliana accessions collected across an 8-year period in six micro-habitats representative of that local population. We then used genome-wide association mapping to identify the single-nucleotide polymorphisms (SNPs) associated with evolved and unevolved traits in each micro-habitat. Finally, we performed a selection scan by testing for temporal differentiation in these SNPs. Phenotypic evolution was consistent across micro-habitats, but its associated genetic bases were largely distinct. Adaptive evolutionary change was most strongly driven by a small number of quantitative trait loci (QTLs) with intermediate degrees of pleiotropy; this pleiotropy was synergistic with the per-trait effect size of the SNPs, increasing with the degree of pleiotropy. In addition, weak selection was detected for frequent micro-habitat-specific QTLs that shape single traits. In this population, A. thaliana probably responded to local warming and increased competition, in part mediated by central regulators of flowering time. This genetic architecture, which includes both synergistic pleiotropic QTLs and distinct QTLs within particular micro-habitats, enables rapid phenotypic evolution while still maintaining genetic variation in wild populations.Lire moins >

Langue :

Anglais

Vulgarisation :

Non

Projet ANR :

Université Fédérale de Toulouse
Towards a Unified theory of biotic Interactions: the roLe of environmental

Collections :

• Évolution, Écologie et Paléontologie (Evo Eco Paleo) - UMR 8198

Source :

Harvested from HAL