Robust and flexible response of Ostreococcus ...
Document type :
Pré-publication ou Document de travail
Title :
Robust and flexible response of Ostreococcus tauri circadian clock to light/dark cycles of varying photoperiod
Author(s) :
Thommen, Quentin [Auteur]
Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
Pfeuty, Benjamin [Auteur]
Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
Corellou, Florence [Auteur]
Laboratoire d'Océanographie Microbienne [LOMIC]
Bouget, François-Yves [Auteur]
Laboratoire d'Océanographie Microbienne [LOMIC]
LEFRANC, Marc [Auteur correspondant]
Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]

Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
Pfeuty, Benjamin [Auteur]
Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
Corellou, Florence [Auteur]
Laboratoire d'Océanographie Microbienne [LOMIC]
Bouget, François-Yves [Auteur]
Laboratoire d'Océanographie Microbienne [LOMIC]
LEFRANC, Marc [Auteur correspondant]

Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
English keyword(s) :
circadian clocks
robustness
flexibility
Ostreococcus tauri
entrainment
robustness
flexibility
Ostreococcus tauri
entrainment
HAL domain(s) :
Sciences du Vivant [q-bio]/Bio-Informatique, Biologie Systémique [q-bio.QM]
Informatique [cs]/Bio-informatique [q-bio.QM]
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Réseaux moléculaires [q-bio.MN]
Informatique [cs]/Bio-informatique [q-bio.QM]
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Réseaux moléculaires [q-bio.MN]
English abstract : [en]
The green microscopic alga Ostreococcus tauri has recently emerged as a promising model for understanding how circadian clocks, which drive the daily biological rythms of many organisms, synchronize to the day/night cycle ...
Show more >The green microscopic alga Ostreococcus tauri has recently emerged as a promising model for understanding how circadian clocks, which drive the daily biological rythms of many organisms, synchronize to the day/night cycle in changing weather and seasons. Here, we analyze translational reporter time series data of its central clock genes CCA1 and TOC1 for a wide range of daylight durations (photoperiods). The variation of temporal profiles with day duration is complex, with the two actors tracking different moments of the day. Nevertheless, all profiles are accurately reproduced by a simple two-gene transcriptional loop model whose parameters are affected by light only through the photoperiod value. We show that this non-intuitive behavior allows the circadian clock to combine flexibility and robustness to daylight fluctuations.Show less >
Show more >The green microscopic alga Ostreococcus tauri has recently emerged as a promising model for understanding how circadian clocks, which drive the daily biological rythms of many organisms, synchronize to the day/night cycle in changing weather and seasons. Here, we analyze translational reporter time series data of its central clock genes CCA1 and TOC1 for a wide range of daylight durations (photoperiods). The variation of temporal profiles with day duration is complex, with the two actors tracking different moments of the day. Nevertheless, all profiles are accurately reproduced by a simple two-gene transcriptional loop model whose parameters are affected by light only through the photoperiod value. We show that this non-intuitive behavior allows the circadian clock to combine flexibility and robustness to daylight fluctuations.Show less >
Language :
Anglais
Source :
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