Title :

Hearing response following internal auditory canal decompression in neurofibromatosis type 2

Author(s) :

Bonne, Nicolas-Xavier [Auteur]
Risoud, Michael [Auteur]
Hoa, Michael [Auteur]
Lemesre, Pierre-Emmanuel [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Aboukais, Rabih [Auteur]
Le Rhun, Emilie [Auteur]
Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Dubrulle, Frederique [Auteur]
Baroncini, Marc [Auteur]
Lejeune, Jean-Paul [Auteur]
Thérapies Assistées par Lasers et Immunothérapies pour l'Oncologie - U 1189 [OncoThAI]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Vincent, Christophe [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]

Journal title :

Neurosurgery

Abbreviated title :

Neurosurgery

Publication date :

2019-03-19

ISSN :

1524-4040

Keyword(s) :

Vestibular schwannoma
Middle fossa craniotomy
Hearing
Deafness
Acoustic neuroma
Neurofibromatosis type 2

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Hearing response following an osteodural decompression of the internal auditory canal (IAC) is controversial. To evaluate the course of auditory brainstem responses (ABRs) and the early hearing response during the first ...
Show more >Hearing response following an osteodural decompression of the internal auditory canal (IAC) is controversial. To evaluate the course of auditory brainstem responses (ABRs) and the early hearing response during the first year following IAC decompression for small to medium-sized vestibular schwannomas occurring in neurofibromatosis type 2 (NF2). Retrospective chart review of middle fossa craniotomy for IAC osteodural decompression in NF2-related vestibular schwannomas. Twelve NF2 patients were operated on from 2011 to 2016 for IAC decompression. All had NF2 according to the Manchester criteria. All had a progressive change of their ABRs documented from the diagnosis of NF2 over a mean period of 6.25 [0.36;10.9] yr. Treatment was proposed to stop hearing progression based on the speech discrimination scores (SDSs; n = 4) or for hearing maintenance (n = 8). In patients with prior hearing progression, hearing responses were observed in 3 of the 4 patients during the first year. One patient kept on progressing. In the hearing maintenance group, the SDSs remained stable. SDSs improved from 85% [20-100] to 92.5% [60-100] on average (n = 12) and from 55% [20-80] to 77.5% [50-100] in the hearing progression group (n = 4). ABRs improved in 4 patients following decompression. IAC decompression allows early objective hearing responses in select patients. We suggest that the procedure should be offered to patients with hearing progression based on their SDSs and/or associated progressive increases in their wave III and V latencies on ABRs.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008
• Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
• Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189

Submission date :

2021-01-20T15:59:17Z
2023-04-21T10:44:11Z
2024-01-22T08:49:49Z