Title :

Intratemporal facial nerve schwannomas: multicenter experience of 80 cases

Author(s) :

Loos, Elke [Auteur]
Verhaert, Nicolas [Auteur]
Darrouzet, Vincent [Auteur]
Godey, Benoit [Auteur]
Linder, Thomas [Auteur]
Vincent, Christophe [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Lavieille, Jean Pierre [Auteur]
Schmerber, Sebastien [Auteur]
Lescanne, Emmanuel [Auteur]
Trabalzini, Franco [Auteur]
De Foer, Bert [Auteur]
Van Havenbergh, Tony [Auteur]
Somers, Thomas [Auteur]

Journal title :

European archives of oto-rhino-laryngology . official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) . affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Abbreviated title :

Eur Arch Otorhinolaryngol

Publication date :

2020-04-11

ISSN :

1434-4726

Keyword(s) :

Hearing
Schwannoma
Neuroma
Facial nerve
Skull base

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

OBJECTIVE: To provide more data on the clinical presentation and natural evolution of facial nerve schwannomas and to provide guidance for therapeutic decision making. METHODS: A retrospective case review of eighty patients ...
Show more >OBJECTIVE: To provide more data on the clinical presentation and natural evolution of facial nerve schwannomas and to provide guidance for therapeutic decision making. METHODS: A retrospective case review of eighty patients diagnosed with a facial nerve schwannoma between 1990 and 2018 in ten tertiary referral centers in Europe was performed. Patients' demographics, symptomatology, audiometry, anatomical site (segments involved), size and whenever possible volume measurement were registered. RESULTS: At presentation, transient or persistent facial palsy was the most common symptom, followed by hearing loss. The schwannoma involved more than one segment in the majority of the patients with the geniculate ganglion being most commonly involved. Initial treatment consisted of a wait and scan approach in 67.5%, surgery in 30% and radiation therapy in 2.5% of the patients. Tympanic segment schwannomas caused mainly conductive hearing loss and were more prone to develop facial palsy at follow-up. Internal auditory canal or cerebellopontine angle schwannomas presented with significantly more sensorineural hearing loss. CONCLUSIONS: Although modern imaging has improved diagnosis of this tumor, choosing the best treatment modality remains a real challenge. Based on the literature review and current findings, more insights into the clinical course and the management of facial nerve schwannomas are provided.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Submission date :

2021-01-20T15:59:22Z