Title :

Parkinson’s-disease-related changes in the behavioural synergy between eye movements and postural movements

Author(s) :

Bonnet, Cédrick T. [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Delval, Arnaud [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Singh, Tarkeshwar [Auteur]
Pennsylvania State University [Penn State]
DEFEBVRE, Luc [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Journal title :

European Journal of Neuroscience

Volume number :

54

Pages :

5161-5172

Publication date :

2021-06-14

English keyword(s) :

Parkinson's disease-related impairments
automatic vs. higher order behaviours
eye and postural movements
synergic model
visual performance

HAL domain(s) :

Sciences cognitives

English abstract : [en]

Patients with Parkinson’s disease (PD patients) have been shown to exhibit abnormally low levels of synergy in their posture control. The goal of this study is to determine how synergic interactions between vision and ...
Show more >Patients with Parkinson’s disease (PD patients) have been shown to exhibit abnormally low levels of synergy in their posture control. The goal of this study is to determine how synergic interactions between vision and posture are affected in PD patients. These synergic interactions were expected to be impaired because PD affects the basal ganglia, which are involved in the modulation of both types of movement. Twenty patients (mean age: 60) on levodopa and 20 age-matched-controls (mean age: 61) performed a precise visual task (searching for targets in an image) and an unprecise control task (randomly looking at an image) in which images were projected onto a large panoramic display. Lower back, upper back, head and eye movements were recorded simultaneously. To test behavioural synergies, Pearson correlations between eye and postural movements were analysed. The relationships between eye movements and upper and lower back movements were impaired in the patients. The age-matched controls did not show any significant correlations between eye and postural movements. Overall, our results showed that the PD patients failed to adjust and control their postural stability for success in the visual task. The impaired synergy between eye and postural movements was not related to clinical variables - probably because our patients had early-stage PD. Our results showed that impairments in synergy can occur very early in PD. Hence, the analysis of this synergy might provide a better understanding of postural instability, visual task performance in the upright stance, and perhaps the risk of falls in PD patients.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Administrative institution(s) :

Université de Lille
CNRS
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172
• Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires
Équipe Action, Vision et Apprentissage (AVA)

Submission date :

2021-06-09T12:50:19Z
2021-07-02T07:18:16Z
2021-08-10T08:42:06Z
2021-08-10T08:48:22Z
2021-08-14T19:22:25Z