Experimental evidence for circular inference ...
Document type :
Article dans une revue scientifique
DOI :
PMID :
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Title :
Experimental evidence for circular inference in schizophrenia
Author(s) :
Jardri, Renaud [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Duverne, Sandrine [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Litvinova, Alexandra S. [Auteur]
Lomonosov Moscow State University = Université d'État Lomonossov de Moscou [Moscou] [MSU]
Denève, Sophie [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Duverne, Sandrine [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Litvinova, Alexandra S. [Auteur]
Lomonosov Moscow State University = Université d'État Lomonossov de Moscou [Moscou] [MSU]
Denève, Sophie [Auteur]
Laboratoire de Neurosciences Cognitives & Computationnelles [LNC2]
Journal title :
Nature communications
Volume number :
8
Pages :
14218
Publication date :
2017-01-31
ISSN :
2041-1723
HAL domain(s) :
Sciences cognitives
English abstract : [en]
<p>Schizophrenia is a mental disorder characterized by hallucinations and delusions. Here Schizophrenia (SCZ) is a complex mental disorder that may result in some combination ofhallucinations, delusions and disorganized ...
Show more ><p>Schizophrenia is a mental disorder characterized by hallucinations and delusions. Here Schizophrenia (SCZ) is a complex mental disorder that may result in some combination ofhallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls(CTLs) report their level of confidence on a forced-choice task that manipulated the strengthof sensory evidence and prior information. Neither group’s responses can be explained bysimple Bayesian inference. Rather, individual responses are best captured by a modelwith different degrees of circular inference. Circular inference refers to a corruption ofsensory data by prior information and vice versa, leading us to ‘see what we expect’(through descending loops), to ‘expect what we see’ (through ascending loops) or both.Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positivesymptoms. Descending loops correlate with the severity of negative symptoms. Both loopscorrelate with disorganized symptoms. The findings suggest that circular inference mightmediate the clinical manifestations of SCZ.Show less >
Show more ><p>Schizophrenia is a mental disorder characterized by hallucinations and delusions. Here Schizophrenia (SCZ) is a complex mental disorder that may result in some combination ofhallucinations, delusions and disorganized thinking. Here SCZ patients and healthy controls(CTLs) report their level of confidence on a forced-choice task that manipulated the strengthof sensory evidence and prior information. Neither group’s responses can be explained bysimple Bayesian inference. Rather, individual responses are best captured by a modelwith different degrees of circular inference. Circular inference refers to a corruption ofsensory data by prior information and vice versa, leading us to ‘see what we expect’(through descending loops), to ‘expect what we see’ (through ascending loops) or both.Ascending loops are stronger for SCZ than CTLs and correlate with the severity of positivesymptoms. Descending loops correlate with the severity of negative symptoms. Both loopscorrelate with disorganized symptoms. The findings suggest that circular inference mightmediate the clinical manifestations of SCZ.Show less >
Language :
Anglais
Audience :
Non spécifiée
Administrative institution(s) :
Université de Lille
CNRS
CHU Lille
CNRS
CHU Lille
Research team(s) :
Équipe Psychiatrie & Croyance (PsyCHIC)
Submission date :
2019-02-13T14:17:58Z
2020-01-23T08:28:34Z
2020-03-23T14:21:40Z
2020-01-23T08:28:34Z
2020-03-23T14:21:40Z
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