Interaction of language, auditory and ...
Document type :
Article dans une revue scientifique
PMID :
Permalink :
Title :
Interaction of language, auditory and memory brain networks in auditory verbal hallucinations
Author(s) :
Ćurčić-Blake, Branislava [Auteur]
University Medical Center Groningen [Groningen] [UMCG]
Ford, Judith M. [Auteur]
University of California [San Francisco] [UC San Francisco]
Hubl, Daniela [Auteur]
Orlov, Natasza D. [Auteur]
King‘s College London
Sommer, Iris E. [Auteur]
University Medical Center [Utrecht] [UMCU]
Waters, Flavie [Auteur]
The University of Western Australia [UWA]
Allen, Paul [Auteur]
King‘s College London
Jardri, Renaud [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Woodruff, Peter W. [Auteur]
City College [International Faculty of the University of Sheffield]
David, Olivier [Auteur]
Grenoble Institut des Neurosciences [GIN]
Mulert, Christoph [Auteur]
Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg] [UKE]
Woodward, Todd [Auteur]
University of Northern British Columbia [Prince George] [UNBC]
Aleman, André [Auteur]
University of Groningen [Groningen]
University Medical Center Groningen [Groningen] [UMCG]
Ford, Judith M. [Auteur]
University of California [San Francisco] [UC San Francisco]
Hubl, Daniela [Auteur]
Orlov, Natasza D. [Auteur]
King‘s College London
Sommer, Iris E. [Auteur]
University Medical Center [Utrecht] [UMCU]
Waters, Flavie [Auteur]
The University of Western Australia [UWA]
Allen, Paul [Auteur]
King‘s College London
Jardri, Renaud [Auteur]

Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Woodruff, Peter W. [Auteur]
City College [International Faculty of the University of Sheffield]
David, Olivier [Auteur]
Grenoble Institut des Neurosciences [GIN]
Mulert, Christoph [Auteur]
Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg] [UKE]
Woodward, Todd [Auteur]
University of Northern British Columbia [Prince George] [UNBC]
Aleman, André [Auteur]
University of Groningen [Groningen]
Journal title :
Progress in Neurobiology
Abbreviated title :
Progress in Neurobiology
Volume number :
148
Pages :
1-20
Publication date :
2017-01-01
ISSN :
0301-0082
HAL domain(s) :
Sciences cognitives
English abstract : [en]
Auditory verbal hallucinations (AVH) occur in psychotic disorders, but also as a symptom of other conditions and even in healthy people. Several current theories on the origin of AVH converge, with neuroimaging studies ...
Show more >Auditory verbal hallucinations (AVH) occur in psychotic disorders, but also as a symptom of other conditions and even in healthy people. Several current theories on the origin of AVH converge, with neuroimaging studies suggesting that the language, auditory and memory/limbic networks are of particular relevance. However, reconciliation of these theories with experimental evidence is missing. We review 50 studies investigating functional (EEG and fMRI) and anatomic (diffusion tensor imaging) connectivity in these networks, and explore the evidence supporting abnormal connectivity in these networks associated with AVH. We distinguish between functional connectivity during an actual hallucination experience (symptom capture) and functional connectivity during either the resting state or a task comparing individuals who hallucinate with those who do not (symptom association studies). Symptom capture studies clearly reveal a pattern of increased coupling among the auditory, language and striatal regions. Anatomical and symptom association functional studies suggest that the interhemispheric connectivity between posterior auditory regions may depend on the phase of illness, with increases in non-psychotic individuals and first episode patients and decreases in chronic patients. Leading hypotheses involving concepts as unstable memories, source monitoring, top-down attention, and hybrid models of hallucinations are supported in part by the published connectivity data, although several caveats and inconsistencies remain. Specifically, possible changes in fronto-temporal connectivity are still under debate. Precise hypotheses concerning the directionality of connections deduced from current theoretical approaches should be tested using experimental approaches that allow for discrimination of competing hypotheses.Show less >
Show more >Auditory verbal hallucinations (AVH) occur in psychotic disorders, but also as a symptom of other conditions and even in healthy people. Several current theories on the origin of AVH converge, with neuroimaging studies suggesting that the language, auditory and memory/limbic networks are of particular relevance. However, reconciliation of these theories with experimental evidence is missing. We review 50 studies investigating functional (EEG and fMRI) and anatomic (diffusion tensor imaging) connectivity in these networks, and explore the evidence supporting abnormal connectivity in these networks associated with AVH. We distinguish between functional connectivity during an actual hallucination experience (symptom capture) and functional connectivity during either the resting state or a task comparing individuals who hallucinate with those who do not (symptom association studies). Symptom capture studies clearly reveal a pattern of increased coupling among the auditory, language and striatal regions. Anatomical and symptom association functional studies suggest that the interhemispheric connectivity between posterior auditory regions may depend on the phase of illness, with increases in non-psychotic individuals and first episode patients and decreases in chronic patients. Leading hypotheses involving concepts as unstable memories, source monitoring, top-down attention, and hybrid models of hallucinations are supported in part by the published connectivity data, although several caveats and inconsistencies remain. Specifically, possible changes in fronto-temporal connectivity are still under debate. Precise hypotheses concerning the directionality of connections deduced from current theoretical approaches should be tested using experimental approaches that allow for discrimination of competing hypotheses.Show less >
Language :
Anglais
Audience :
Non spécifiée
Administrative institution(s) :
Université de Lille
CNRS
CHU Lille
CNRS
CHU Lille
Research team(s) :
Équipe Psychiatrie & Croyance (PsyCHIC)
Submission date :
2019-02-13T14:17:59Z
2020-03-09T14:55:46Z
2020-03-19T12:00:38Z
2020-03-20T08:13:59Z
2020-03-09T14:55:46Z
2020-03-19T12:00:38Z
2020-03-20T08:13:59Z
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