Titre :

Endoscopic balloon dilation of colorectal strictures complicating crohn's disease: a multicenter study

Auteur(s) :

Tilmant, Marion [Auteur]
Serrero, Melanie [Auteur]
Poullenot, Florian [Auteur]
Bouguen, Guillaume [Auteur]
Pariente, Benjamin [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Altwegg, Romain [Auteur]
Basile, Paul [Auteur]
Filippi, Jerome [Auteur]
Vanelslander, Pierre [Auteur]
Buisson, Anthony [Auteur]
Desjeux, Ariane [Auteur]
Laharie, David [Auteur]
Le Balch, Eric [Auteur]
Nachury, Maria [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Boivineau, Lucile [Auteur]
Savoye, Guillaume [Auteur]
Hebuterne, Xavier [Auteur]
Poincloux, Laurent [Auteur]
Vuitton, Lucine [Auteur]
Brazier, Franck [Auteur]
Yzet, Clara [Auteur]
Lamrani, Adnane [Auteur]
Peyrin-Biroulet, Laurent [Auteur]
Fumery, Mathurin [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Titre de la revue :

Clinics and research in hepatology and gastroenterology

Nom court de la revue :

Clin Res Hepatol Gastroenterol

Date de publication :

2020-11-16

ISSN :

2210-741X

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

BACKGROUND: While endoscopic balloon dilation (EBD) is widely used to manage ileal strictures, EBD of colorectal strictures remains poorly investigated in Crohn's disease (CD). METHODS: We performed a retrospective study ...
Lire la suite >BACKGROUND: While endoscopic balloon dilation (EBD) is widely used to manage ileal strictures, EBD of colorectal strictures remains poorly investigated in Crohn's disease (CD). METHODS: We performed a retrospective study that included all consecutive CD patients who underwent EBD for native or anastomotic colorectal strictures in 9 tertiary centers between 1999 and 2018. Factors associated with EBD failure were also investigated by logistic regression. RESULTS: Fifty-seven patients (25 women, median age: 36 years (InterQuartile Range, 31-48) were included. Among the 60 strictures, 52 (87%) were native, 39 (65%) measured < 5 cm and the most frequent location was the left colon (27%). Fifty-seven (95%) were non-passable by the scope and 35 (58%) were ulcerated. Among the 161 EBDs performed (median number of dilations per stricture: 2, IQR 1-3), technical and clinical success were achieved for 79% (n = 116/147) and 77% (n = 88/115), respectively. One perforation occurred (0.6% per EDB and 2% per patient). After a median follow-up of 4.3 years (IQR 2.0-8.4), 24 patients (42%) underwent colonic resection and 24 (42%) were asymptomatic without surgery. One colon lymphoma and one colorectal cancer were diagnosed (3.5% of patients) from endoscopic biopsies and at the time of surgery, respectively. No factor was associated with technical or clinical success. CONCLUSIONS: EDB of CD-associated colorectal strictures is feasible, efficient and safe, with more than 40% becoming asymptomatic without surgery.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2021-07-06T12:44:58Z