Monitoring of inflammatory bowel disease in 2019: a french consensus for clinical practice

Bonnaud, Guillaume; Bouhnik, Yoram; Hagege, Herve; Hebuterne, Xavier; Pariente, Benjamin; Roblin, Xavier; Peyrin-Biroulet, Laurent

Document type :

Article dans une revue scientifique: Article de synthèse/Review paper

DOI :

10.1016/j.dld.2020.03.033

PMID :

32402743

Permalink :

http://hdl.handle.net/20.500.12210/40544

Title :

Monitoring of inflammatory bowel disease in 2019: a french consensus for clinical practice

Author(s) :

Bonnaud, Guillaume [Auteur]
Hôpital Ambroise Paré [AP-HP]
Bouhnik, Yoram [Auteur]
Hôpital Beaujon [AP-HP]
Hagege, Herve [Auteur]
CHI Créteil
Hebuterne, Xavier [Auteur]
Hôpital l'Archet
Pariente, Benjamin [Auteur]

Université de Lille
Roblin, Xavier [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Peyrin-Biroulet, Laurent [Auteur]
Nutrition-Génétique et Exposition aux Risques Environnementaux [NGERE]
Centre Hospitalier Universitaire de Nancy [CHU Nancy]

Journal title :

Digestive and Liver Disease

Abbreviated title :

Dig Liver Dis

Publication date :

2020-05-05

ISSN :

1878-3562

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

For inflammatory bowel disease, traditional dose escalation approaches that are based on clinical symptoms are being replaced by more aggressive treat-to-target approaches, in which treatment is adjusted promptly when ...
Show more >For inflammatory bowel disease, traditional dose escalation approaches that are based on clinical symptoms are being replaced by more aggressive treat-to-target approaches, in which treatment is adjusted promptly when predefined clinical and mucosal targets are not met. There is, however, an ongoing need to combine up-to-date treat-to-target strategies with easy-to-implement recommendations. Herein, we present consensus-recommendations for treatment targets that reflect current best practices in France. Methods Thirty-four gastroenterologists practicing in France participated in a meeting during which consensus statements about treat-to-target strategies for following patients with Crohn's disease (CD) and ulcerative colitis were developed. Targets, their definitions, and the timeframes for reaching them were defined. Consensus was defined as ≥66% of experts agreeing with a statement. Results For both diseases, the agreed targets were: patient related outcomes on disease (PRO-1), patient related outcomes on gastrointestinal symptoms (PRO-2), endoscopic healing and biomarkers of inflammation. Nutritional status has been defined as a target for CD only. Histological healing and transmural healing were not defined as targets. Deadlines to achieve targets and monitoring frequency have been agreed as well. Conclusions These consensus statements provide simple, easy-to-follow guidelines that should help gastroenterologists in France implement treat-to-target approaches, optimize treatments, and thus, reduce the burden of disease.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2021-07-06T12:45:08Z
2024-02-06T12:39:34Z

Version	Link	Modification date
2	20.500.12210/40544*	2024-02-06T12:37:39Z
1	20.500.12210/40544.1	2021-07-06T12:45:08Z

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Monitoring of inflammatory bowel disease ...

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