Title :

Mesh repair in crohn''s disease: a case-matched multicenter study in 234 patients

Author(s) :

Beyer-Berjot, Laura [Auteur]
Hôpital Nord [CHU - APHM]
Moszkowicz, David [Auteur]
UFR Sciences de la santé Simone Veil [UVSQ Santé]
Service de chirurgie générale, digestive et oncologique [CHU Ambroise-Paré]
Bridoux, Valérie [Auteur]
Service de Chirurgie Digestive [CHU Rouen]
Schneider, Lucil [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Theuil, Luca [Auteur]
CHU Montpellier = Montpellier University Hospital
Francois, Yves [Auteur]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Abdalla, Solafah [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Cotte, Eddy [Auteur]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Maggiori, Leon [Auteur]
Hôpital Beaujon [AP-HP]
Brouquet, Antoine [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Souche, Francois-Regis [Auteur]
Hôpital Saint Eloi [CHU Montpellier]
Zerbib, Philippe [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Tuech, Jean-Jacques [Auteur]
CHU Rouen
Panis, Yves [Auteur]
Hôpital Beaujon [AP-HP]
Berdah, Stephane [Auteur]
Hôpital Nord [CHU - APHM]

Journal title :

World Journal of Surgery

Abbreviated title :

World J Surg

Publication date :

2020-02-27

ISSN :

1432-2323

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

There are no specific guidelines for ventral hernia management in Crohn's disease (CD) patients. We aimed to assess the risk of septic morbidity after mesh repair in CD. This was a retrospective multicentre study comparing ...
Show more >There are no specific guidelines for ventral hernia management in Crohn's disease (CD) patients. We aimed to assess the risk of septic morbidity after mesh repair in CD. This was a retrospective multicentre study comparing CD and non-CD patients undergoing mesh repair for ventral hernia (primary or incisional hernia). Controls were matched 1:1 for the presence of a stoma, history of surgical sepsis, hernia size and Ventral Hernia Working Group (VHWG) score. All demographic, pre-, intra- and postoperative data were retrieved, including long-term data. We included 234 patients, with 114 CD patients. Both groups had comparable VHWG scores (p = 0.12), hernia sizes (p = 0.11), ASA scores ≥ 3 (p = 0.70), body mass index values (p = 0.14), presence of stoma (CD 21.9% vs. controls 15%, p = 0.16), history of sepsis (14% vs. 6.7%, p = 0.23), rates of malnutrition (4.4% vs. 1.7%, p = 0.46), rates of incisional hernia (93% vs. 95%, p = 0.68) and concomitant procedures (18.4% vs. 11.7%, p = 0.12). CD patients carried a higher risk of postoperative septic morbidity (18.4% vs. 5%, p = 0.001), entero-prosthetic fistula (7% vs. 0, p < 0.01) and mesh withdrawals (5.3% vs. 0, p = 0.011). Ventral hernia recurrence rates were similar (14% vs. 8.3%, p = 0.15). In the univariate analysis, the risk factors for septic morbidity were CD (p = 0.001), malnutrition (p = 0.004), use of biological mesh (p < 0.0001) and concomitant procedure (p = 0.004). The mesh position, the means used for mesh fixation as well as the presence of a stoma were not identified as risk factors. CD seems to be a risk factor for septic morbidity after mesh repair.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2021-07-06T12:45:31Z
2024-03-29T16:09:33Z