Title :

Factors associated with success and failure of weaning children from prolonged enteral nutrition: a retrospective cohort study

Author(s) :

Dipasquale, Valeria [Auteur]
Hôpital Jeanne de Flandre [Lille]
Lecoeur, Katia [Auteur]
Hôpital Jeanne de Flandre [Lille]
Aumar, Madeleine [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Guimber, Dominique [Auteur]
Hôpital Jeanne de Flandre [Lille]
Coopman, Stephanie [Auteur]
Hôpital Jeanne de Flandres
Nicolas, Audrey [Auteur]
Hôpital Jeanne de Flandres
Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
gottrand, Fréderic [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE (Ex-Liric)]
Ley, Delphine [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Journal title :

Journal of pediatric gastroenterology and nutrition

Abbreviated title :

J. Pediatr. Gastroenterol. Nutr.

Volume number :

72

Pages :

135-140

Publisher :

Wolters Kluwer

Publication date :

2020-08-17

ISSN :

1536-4801

Keyword(s) :

outcome
outpatient
pediatrics
tube feeding
weaning

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The aims of the present study were to assess the efficacy of a tube weaning program, and to identify factors associated with success and failure. This was a retrospective cohort study including all pediatric patients on ...
Show more >The aims of the present study were to assess the efficacy of a tube weaning program, and to identify factors associated with success and failure. This was a retrospective cohort study including all pediatric patients on enteral nutrition (EN) for ≥6 months for whom at least 1 attempt of weaning was performed in a single tertiary referral center from 2012 to 2017, with a minimum follow-up of 6 months after EN discontinuation. Weaning program was individualized to each child. Weaning success was defined a priori. Factors associated with success were investigated using multivariate analysis. Ninety-four patients were enrolled, in whom a total of 114 attempts of weaning were performed at a median age of 51 ± 40 months. Success was achieved in 80 attempts (success rate of 70%). One hundred three (92%) weaning attempts were performed at home with a follow-up in the outpatient clinic, mostly (74%) by a progressive (>1 month) reduction of tube feeding. Patients who required psychological support during weaning had more failures than patients who did not (odds ratio = 5.7, 95% confidence interval [1.2-27.0], P = 0.03). The presence of impaired oral feeding skills at the time of EN discontinuation was also predictive of failure (odds ratio = 6.2, 95% confidence interval [0.05-0.5], P = 0.005). Our progressive, mostly outpatient-based, patient-tailored program of weaning from EN is effective for tube-dependent children. Children who need psychological support during weaning and those who present impaired oral feeding skills represent a subgroup of at-risk patients for whom alternative weaning strategies may need to be considered.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2021-07-06T12:48:58Z
2023-03-22T10:10:34Z