Secondary itp in adults
Document type :
Article dans une revue scientifique: Article original
PMID :
Permalink :
Title :
Secondary itp in adults
Author(s) :
Michel, Marc [Auteur]
Service de médecine interne [Mondor]
Lega, J.-C. [Auteur]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Terriou, Louis [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Service de médecine interne [Lille]
Service de médecine interne [Mondor]
Lega, J.-C. [Auteur]
Centre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
Terriou, Louis [Auteur]

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Service de médecine interne [Lille]
Journal title :
La Revue de Médecine Interne
Abbreviated title :
Rev Med Interne
Publication date :
2020-10-31
ISSN :
1768-3122
Keyword(s) :
Chronic lymphocytic leukemia
Systemic lupus
Secondary ITP
Immunological thrombocytopenic purpura
Variable common immune deficiency
Systemic lupus
Secondary ITP
Immunological thrombocytopenic purpura
Variable common immune deficiency
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Secondary forms of immune thrombocytopenia (ITP) represent approximately 20% of all ITP cases in adulthood and this rate increases with age. Since some causes may influence both the prognosis and outcome but also the ...
Show more >Secondary forms of immune thrombocytopenia (ITP) represent approximately 20% of all ITP cases in adulthood and this rate increases with age. Since some causes may influence both the prognosis and outcome but also the management of ITP, a minimal workup must be performed at ITP diagnosis to look for an associated or underlying cause. Among adults, B-cell lymphomas and mainly chronic lymphocytic leukemia, systemic auto-immune diseases such as systemic lupus or primary immunodeficiencies mainly represented by common variable immunodeficiency are the most frequent causes of secondary ITP. Whereas first-line therapy used for secondary ITP is usually similar to the one commonly used in primary ITP and relies mostly on corticosteroids±intravenous immunoglobulin according to the severity of bleeding, second and third-line treatments must take into account the type and degree of activity of the underlying disease.Show less >
Show more >Secondary forms of immune thrombocytopenia (ITP) represent approximately 20% of all ITP cases in adulthood and this rate increases with age. Since some causes may influence both the prognosis and outcome but also the management of ITP, a minimal workup must be performed at ITP diagnosis to look for an associated or underlying cause. Among adults, B-cell lymphomas and mainly chronic lymphocytic leukemia, systemic auto-immune diseases such as systemic lupus or primary immunodeficiencies mainly represented by common variable immunodeficiency are the most frequent causes of secondary ITP. Whereas first-line therapy used for secondary ITP is usually similar to the one commonly used in primary ITP and relies mostly on corticosteroids±intravenous immunoglobulin according to the severity of bleeding, second and third-line treatments must take into account the type and degree of activity of the underlying disease.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
Inserm
Université de Lille
Inserm
Université de Lille
Submission date :
2021-07-06T12:49:19Z
2024-01-29T10:18:11Z
2024-01-29T10:18:11Z