Cognition - the core of major depressive disorder

Polosan, M.; Lemogne, C.; Jardri, Renaud; Fossati, P.

Document type :

Article dans une revue scientifique

DOI :

10.1016/S0013-7006(16)30014-8

PMID :

26879254

Permalink :

http://hdl.handle.net/20.500.12210/4085

Title :

Cognition - the core of major depressive disorder

Author(s) :

Polosan, M. [Auteur]
Lemogne, C. [Auteur]
Jardri, Renaud [Auteur]

Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Fossati, P. [Auteur]

Journal title :

L’Encéphale

Abbreviated title :

Encephale

Volume number :

Pages :

1S3-11

Publication date :

2016-02

ISSN :

0013-7006

HAL domain(s) :

Sciences cognitives

English abstract : [en]

Cognitive deficits have been only recently recognized as a major phenotype determinant of major depressive disorder, although they are an integral part of the definition of the depressive state. Congruent evidence suggest ...
Show more >Cognitive deficits have been only recently recognized as a major phenotype determinant of major depressive disorder, although they are an integral part of the definition of the depressive state. Congruent evidence suggest that these cognitive deficits persist beyond the acute phase and may be identified at all ages. The aim of the current study was to review the main meta-analyses on cognition and depression, which encompasses a large range of cognitive domains. Therefore, we discuss the "cold" (attention, memory, executive functions) and "hot" (emotional bias) cognitive impairments in MDD, as well as those of social cognition domains (empathy, theory of mind). Several factors interfere with cognition in MDD such as clinical (melancholic, psychotic...) features, age, age of onset, illness severity, medication and comorbid condition. As still debated in the literature, the type of relationship between the severity of cognitive symptoms and functioning in depression is detailed, thus highlighting their predictive value of functional outcome, independently of the affective symptoms. A better identification of the cognitive deficits in MDD and a monitoring of the effects of different treatments require appropriate instruments, which may be developed by taking advantage of the increasing success of computing tools. Overall, current data suggest a core role for different cognitive deficits in MDD, therefore opening new perspectives for optimizing the treatment of depression.Show less >

Language :

Anglais

Audience :

Non spécifiée

Administrative institution(s) :

Université de Lille
CNRS
CHU Lille

Collections :

Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Research team(s) :

Équipe Psychiatrie & Croyance (PsyCHIC)

Submission date :

2019-02-13T14:48:09Z
2019-12-03T16:17:29Z

Version	Link	Modification date
2	20.500.12210/4085*	2019-12-03T16:16:23Z
1	20.500.12210/4085.1	2019-02-13T14:48:09Z

Cognition - the core of major depressive disorder

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Cognition - the core of major depressive disorder

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RIS