Two-dimensional mass spectrometry: new ...
Document type :
Autre communication scientifique (congrès sans actes - poster - séminaire...)
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Title :
Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry
Author(s) :
van Agthoven, Maria [Auteur]
Lam, Yuko [Auteur]
O’Connor, Peter [Auteur]
Rolando, Christian [Auteur]
Miniaturisation pour la Synthèse, l’Analyse et la Protéomique - UAR 3290 [MSAP]
Delsuc, Marc-André [Auteur]
Centre de Biochimie Structurale [Montpellier] [CBS]
Lam, Yuko [Auteur]
O’Connor, Peter [Auteur]
Rolando, Christian [Auteur]

Miniaturisation pour la Synthèse, l’Analyse et la Protéomique - UAR 3290 [MSAP]
Delsuc, Marc-André [Auteur]
Centre de Biochimie Structurale [Montpellier] [CBS]
Publisher :
Springer Verlag (Germany)
Publication date :
2019-04
English keyword(s) :
Mass spectrometry
Two dimensional
Fourier transform
Fourier transform ion cyclotron resonance mass spectrometry
Tandem mass spectrometry
Two dimensional
Fourier transform
Fourier transform ion cyclotron resonance mass spectrometry
Tandem mass spectrometry
HAL domain(s) :
Chimie
Chimie/Chimie analytique
Chimie/Chimie analytique
English abstract : [en]
Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions ...
Show more >Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions of all compounds in a complex sample. Fragmentation caused by ion–neutral, ion–electron, or ion–photon interactions leads to more detailed structural information on compounds. The most often used method to correlate compounds and their fragment ions is to isolate the precursor ions from the sample before fragmentation. Two-dimensional mass spectrometry (2D MS) offers a method to correlate precursor and fragment ions without requiring precursor isolation. 2D MS therefore enables easy access to the fragmentation patterns of all compounds from complex samples. In this article, the principles of FT-ICR MS are reviewed and the 2D MS experiment is explained. Data processing for 2D MS is detailed, and the interpretation of 2D mass spectra is described.Show less >
Show more >Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions of all compounds in a complex sample. Fragmentation caused by ion–neutral, ion–electron, or ion–photon interactions leads to more detailed structural information on compounds. The most often used method to correlate compounds and their fragment ions is to isolate the precursor ions from the sample before fragmentation. Two-dimensional mass spectrometry (2D MS) offers a method to correlate precursor and fragment ions without requiring precursor isolation. 2D MS therefore enables easy access to the fragmentation patterns of all compounds from complex samples. In this article, the principles of FT-ICR MS are reviewed and the 2D MS experiment is explained. Data processing for 2D MS is detailed, and the interpretation of 2D mass spectra is described.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Source :
Submission date :
2021-07-26T10:59:35Z
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