Title :

The antimicrobial peptide oranicin P16 isolated from Trichosporon asahii ICVY021, found in camel milk's, inhibits Kocuria rhizophila

Author(s) :

Ider, Soufian [Auteur]
Transfrontalière BioEcoAgro - UMR 1158 [BioEcoAgro]
Belguesmia, Yanath [Auteur correspondant]
Transfrontalière BioEcoAgro - UMR 1158 [BioEcoAgro]
Cazals, Guillaume [Auteur]
Boukherroub, Rabah [Auteur]
NanoBioInterfaces - IEMN [NBI - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Coucheney, Françoise [Auteur]
Transfrontalière BioEcoAgro - UMR 1158 [BioEcoAgro]
Kihal, Mabrouk [Auteur]
Enjalbal, Christine [Auteur]
Drider, Djamel [Auteur]
Transfrontalière BioEcoAgro - UMR 1158 [BioEcoAgro]

Journal title :

Food Bioscience

Publisher :

Elsevier

Publication date :

2020-08

ISSN :

2212-4292

English keyword(s) :

Trichosporon asahii
Yeast antimicrobial peptide
Kocuria rhizophila
Camel milk

HAL domain(s) :

Sciences du Vivant [q-bio]/Alimentation et Nutrition

English abstract : [en]

Six Trichosporon asahii strains designated ICVY021, ICVY022, ICVY023, ICVY024, ICVY025 and ICVY026 were isolated from camel milk and studied for their inhibitory activities against a large number of fungi and bacteria as ...
Show more >Six Trichosporon asahii strains designated ICVY021, ICVY022, ICVY023, ICVY024, ICVY025 and ICVY026 were isolated from camel milk and studied for their inhibitory activities against a large number of fungi and bacteria as target organisms. Only strain ICVY021 was able to inhibit Kocuria rhizophila CIP 53.45, through production of an extracellular heat-stable, proteinaceous antibacterial peptide, with partial amino acid sequences of PPFPK and CTHV(L/I)(K/Q) or TCHV(L/I)(K/Q), determined using LC/MS/MS. This peptide, named oranicin P16, was thought to impede the cell-division mechanism. The anti-K. rhizophila activity was confirmed, in situ , using skim milk as a food matrix. T. asahii ICVY021 did not show any hemolytic activity or any cytotoxicity effect against eukaryotic Caco-2 cells. T. asahii ICVY021 was sensitive to azoles antifungal compounds, but not to 5-fluorocytosine and anidulafungin.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Institut d'Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520

Source :

Harvested from HAL