Protein digestion and energy homeostasis: ...
Document type :
Article dans une revue scientifique
Permalink :
Title :
Protein digestion and energy homeostasis: How generated peptides may impact intestinal hormones?
Author(s) :
Caron, Juliette [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Domenger, Dorothee [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Belguesmia, Yanath [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Kouach, Mostafa [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
LESAGE, JEAN [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Goossens, Jean-Francois [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Dhulster, Pascal [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Ravallec, Rozenn [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cudennec, Benoit [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Domenger, Dorothee [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Belguesmia, Yanath [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Kouach, Mostafa [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
LESAGE, JEAN [Auteur]

Environnement périnatal et croissance - EA 4489 [EPS]
Goossens, Jean-Francois [Auteur]

Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Dhulster, Pascal [Auteur]

Institut Charles Viollette (ICV) - EA 7394 [ICV]
Ravallec, Rozenn [Auteur]

Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cudennec, Benoit [Auteur]

Institut Charles Viollette (ICV) - EA 7394 [ICV]
Journal title :
Food Research International
Abbreviated title :
Food Res. Int.
Volume number :
88
Pages :
310-318
Publication date :
2016
ISSN :
0963-9969
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The aim of the present study is to investigate how peptides released by gastrointestinal (GI) digestion of one dietary protein can interact with regulating processes of food intake. An in vitro GI digestion of bovine ...
Show more >The aim of the present study is to investigate how peptides released by gastrointestinal (GI) digestion of one dietary protein can interact with regulating processes of food intake. An in vitro GI digestion of bovine haemoglobin was carried out and the bioactivity of the digests on CCK and GLP-1 secretion and dipeptidyl peptidase IV (DPP-IV) activity was measured. Intestinal digests exhibited the most potent action on gut hormone release and DPP-IV activity inhibition. They also had the ability to promote hormone gene expression. As a conclusion, two fractions from final intestinal digest led to the greatest GLP-1 secretion increase and DPP-IV activity inhibition. These findings could be very useful in obesity and T2D management research.Show less >
Show more >The aim of the present study is to investigate how peptides released by gastrointestinal (GI) digestion of one dietary protein can interact with regulating processes of food intake. An in vitro GI digestion of bovine haemoglobin was carried out and the bioactivity of the digests on CCK and GLP-1 secretion and dipeptidyl peptidase IV (DPP-IV) activity was measured. Intestinal digests exhibited the most potent action on gut hormone release and DPP-IV activity inhibition. They also had the ability to promote hormone gene expression. As a conclusion, two fractions from final intestinal digest led to the greatest GLP-1 secretion increase and DPP-IV activity inhibition. These findings could be very useful in obesity and T2D management research.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
INRA
ISA
Univ. Artois
Univ. Littoral Côte d’Opale
CHU Lille
INRA
ISA
Univ. Artois
Univ. Littoral Côte d’Opale
Collections :
Research team(s) :
Modélisation biopharmaceutique et pharmacocinétique
Submission date :
2019-02-26T17:11:52Z
2022-01-19T11:03:23Z
2022-01-19T11:03:23Z