Title :

Caenorhabditis elegans as a model organism for aging: relevance, limitations and future.

Author(s) :

Litke, Rachel [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Boulanger, Eric [Auteur]
Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
Lille Inflammation Research International Center (LIRIC) - U995
Fradin, Chantal [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995

Journal title :

Médecine/Sciences

Abbreviated title :

Med Sci (Paris)

Volume number :

34

Pages :

571-579

Publication date :

2018-06

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Aging is a physiological and complex process associated with increasing age of living organisms. Simple model organisms have brought significant advances in our understanding of the aging process. Caenorhabditis elegans, ...
Show more >Aging is a physiological and complex process associated with increasing age of living organisms. Simple model organisms have brought significant advances in our understanding of the aging process. Caenorhabditis elegans, a nematode originally used to establish the genetic and molecular basis of development, has become one of the leading model organisms for research on aging. This invertebrate has allowed identifying a connection between cellular signaling pathways and longevity. Although C. elegans is not suitable for analysis of the complete process of human aging, it remains a model of choice to analyze specific aging mechanisms and phenotypes.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Fungal associated invasive and inflammatory diseases
IBD and environnemental factors : epidemiology and functional analyses
Glycation from inflammation to aging

Submission date :

2019-03-01T14:08:02Z
2024-02-29T09:36:51Z