Titre :

An immunological link between Candida albicans colonization and Crohn's disease

Auteur(s) :

Gerard, Romain [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Sendid, Boualem [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Colombel, Jean-Frederic [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Poulain, Daniel [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Jouault, Thierry [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]

Titre de la revue :

Critical reviews in microbiology

Nom court de la revue :

Crit. Rev. Microbiol.

Numéro :

41

Pagination :

135-139

Date de publication :

2013-07-16

ISSN :

1040-841X

Mot(s)-clé(s) :

innate/adaptive immune response
pathogen associated molecular patterns
Antigens
inflammation

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

The etiology of Crohn’s disease (CD), an autoimmune, inflammatory bowel disease (IBD) which affects approximately one million people in Europe, is still unclear. Nevertheless, it is widely accepted that CD could result ...
Lire la suite >The etiology of Crohn’s disease (CD), an autoimmune, inflammatory bowel disease (IBD) which affects approximately one million people in Europe, is still unclear. Nevertheless, it is widely accepted that CD could result from an inappropriate inflammatory response to intestinal microorganisms in a genetically susceptible host. Most studies to date have concerned the involvement of bacteria in disease progression. In addition to bacteria, there appears to be a possible link between the commensal yeast Candida albicans and disease development. In this review, in an attempt to link the gut colonization process and the development of CD, we describe the different pathways that are involved in the progression of CD and in the host response to C. albicans, making the yeast a possible initiator of the inflammatory process observed in this IBD.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Projet Européen :

Fungi in the setting of inflammation, allergy and autoimmune diseases:Translating basic science into clinical practices

Établissement(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Équipe(s) de recherche :

Inflammatory digestive disease : pathophysiology and therapeutic targets developement
Fungal associated invasive and inflammatory diseases
Nutritional modulation of inflammation and infection

Date de dépôt :

2019-03-01T14:46:38Z
2023-05-03T09:19:35Z