Title :

Exons, introns and DNA thermodynamics

Author(s) :

Carlon, Enrico [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Malki, Mehdi Lejard [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Blossey, Ralf [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]

Journal title :

Physical Review Letters

Pages :

178101

Publisher :

American Physical Society

Publication date :

2005

ISSN :

0031-9007

HAL domain(s) :

Physique [physics]/Matière Condensée [cond-mat]/Mécanique statistique [cond-mat.stat-mech]
Physique [physics]/Physique [physics]/Biophysique [physics.bio-ph]

English abstract : [en]

The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the ...
Show more >The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from the genomic DNA by removing all introns. A clear correspondence is observed between exons and melting domains. This finding may provide new insights in the physical mechanisms underlying the evolution of genes.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Non spécifiée

Popular science :

Non

Comment :

4 pages, 8 figures - Final version as published. See also Phys. Rev. Focus 15, story 17

Collections :

• Institut d'Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520

Source :

Harvested from HAL