Exons, introns and DNA thermodynamics
Document type :
Article dans une revue scientifique
Title :
Exons, introns and DNA thermodynamics
Author(s) :
Carlon, Enrico [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Malki, Mehdi Lejard [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Blossey, Ralf [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Malki, Mehdi Lejard [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Blossey, Ralf [Auteur]

Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Journal title :
Physical Review Letters
Pages :
178101
Publisher :
American Physical Society
Publication date :
2005
ISSN :
0031-9007
HAL domain(s) :
Physique [physics]/Matière Condensée [cond-mat]/Mécanique statistique [cond-mat.stat-mech]
Physique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
Physique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
English abstract : [en]
The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the ...
Show more >The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from the genomic DNA by removing all introns. A clear correspondence is observed between exons and melting domains. This finding may provide new insights in the physical mechanisms underlying the evolution of genes.Show less >
Show more >The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from the genomic DNA by removing all introns. A clear correspondence is observed between exons and melting domains. This finding may provide new insights in the physical mechanisms underlying the evolution of genes.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Non spécifiée
Popular science :
Non
Comment :
4 pages, 8 figures - Final version as published. See also Phys. Rev. Focus 15, story 17
Source :
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