Title :

Chicory roots for prebiotics and appetite regulation: a pilot study in mice.

Author(s) :

Foure, Marion [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
DUGARDIN, Camille [Auteur]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Foligne, Benoit [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
HANCE, PHILIPPE [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cadalen, Thierry [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Delcourt, Abigael [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Taminiau, Bernard [Auteur]
Université de Liège
Daube, George [Auteur]
Université de Liège
Ravallec, Rozenn [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cudennec, Benoit [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Hilbert, Jean-Louis [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Lucau-Danila, Anca [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]

Journal title :

Journal of Agricultural and Food Chemistry

Abbreviated title :

J. Agric. Food Chem.

Volume number :

66

Pages :

6439–6449

Publication date :

2018-06-27

ISSN :

1520-5118

Keyword(s) :

Cichorium intybus
satiety hormones
metagenetics
metabolomics
prebiotics

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The objectives of this work are to address the prebiotic effects of chicory (Cichorium intybus) together with its possible role in appetite control. We compared nine chicory genotypes in order to determine if variations ...
Show more >The objectives of this work are to address the prebiotic effects of chicory (Cichorium intybus) together with its possible role in appetite control. We compared nine chicory genotypes in order to determine if variations in the content of metabolites in the roasted roots would lead to modifications in release of satiety hormones and in composition of gut microbiota. To this aim, a 5-week dietary-intervention study was achieved using mice fed with distinct chicory-based preparations. A 16S rRNA gene-based metagenetic analysis of fecal microbiota was performed. In vitro gastrointestinal digestions were performed in order to study the effect of chicory intestinal digests on gut hormone regulation in enteroendocrine cells. Firmicutes/Bacteroidetes ratio and gut bacterial groups, such as Alloprevotella, Blautia, Alistipes, and Oscillibacter, were found to be modulated by chicory. On the other hand, CCK and GLP-1 satiety hormones were demonstrated to be significantly increased by chicory in vitro.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille
INRA
ISA
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• BioEcoAgro - UMR-T 1158
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Inflammatory digestive disease : pathophysiology and therapeutic targets developement

Submission date :

2019-03-01T15:24:50Z
2024-02-12T14:42:53Z