Understanding antral contraction in human ...
Document type :
Autre communication scientifique (congrès sans actes - poster - séminaire...): Poster
Permalink :
Title :
Understanding antral contraction in human stomach through comparison with soft elastic reactor
Author(s) :
Jeantet, Romain [Auteur]
Science et Technologie du Lait et de l'Oeuf [STLO]
Delaplace, Guillaume [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Liu, M. [Auteur]
Xiao, J. [Auteur]
Dupont, Didier [Auteur]
Science et Technologie du Lait et de l'Oeuf [STLO]
Chen, X. [Auteur]
Science et Technologie du Lait et de l'Oeuf [STLO]
Delaplace, Guillaume [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Liu, M. [Auteur]
Xiao, J. [Auteur]
Dupont, Didier [Auteur]
Science et Technologie du Lait et de l'Oeuf [STLO]
Chen, X. [Auteur]
Conference title :
6. International Conference on Food Digestion
Conference organizers(s) :
Institut National de Recherche Agronomique (INRA) / AgroCampus Rennes : Science et Technologie du Lait et de l'oeuf (1253)
City :
Grenade
Country :
Espagne
Start date of the conference :
2019-04-02
Keyword(s) :
viscosité
estomac
réacteur
digestion
onde péristaltique
contraction antrale
rhéologie
propriété rhéologique
réacteur élastique
analyse dimensionnelle
estomac
réacteur
digestion
onde péristaltique
contraction antrale
rhéologie
propriété rhéologique
réacteur élastique
analyse dimensionnelle
English keyword(s) :
rheology
reactor
viscosity
ventriculus (stomach)
reactor
viscosity
ventriculus (stomach)
HAL domain(s) :
Sciences du Vivant [q-bio]/Alimentation et Nutrition
Sciences du Vivant [q-bio]/Ingénierie des aliments
Sciences du Vivant [q-bio]/Ingénierie des aliments
English abstract : [en]
Human digestion, a major concern due to the rapid development of nutrition-related chronic diseases,rely apart from enzymatic reactions on homogenization of the gastric content by antral contractions.Although recent CFD ...
Show more >Human digestion, a major concern due to the rapid development of nutrition-related chronic diseases,rely apart from enzymatic reactions on homogenization of the gastric content by antral contractions.Although recent CFD studies made it possible to explore the influence of the rheologicalproperties of the gastric content on the efficiency of gastric mixing, this key step is yet far from beingfully understood.ObjectiveThis work aims at discussing the influences of contraction frequency and viscosity of the digestain human gastric mixing by comparison with the mixing efficiency of an innovative soft elastic reactor(SER), that induces mixing by vibration of its wall in a similar way as antral contraction waves(ACWs) promote stomach motility.MethodologyIn this view, the SER mixing curve, recently established by Delaplace et al. (2018) using a dimensionalanalysis approach, was considered in order to determine the flow regime under which thegastric mixing of foods (viscosity ranging from 10-3 to 1 Pa.s) was performedMain findingsIt was shown that depending on the viscosity of the SER/stomach content and the amplitude of penetration/ACWs, the number of strikes/contractions required to achieve homogenization was largelydifferent. Moreover, the operating points of SER and ACWs mixing were close, justifying the comparisonbetween both reactors.ConclusionBased on this, the level of mechanical solicitation provided by human peristalsis was shown to benot as high as expected, and the mixing performance of distal region, confined in laminar regime,was found limited and not only due to mechanical solicitations. Further efforts are needed to investigatethe role of other physiological processes such as gastric secretions and gastric emptying inmixing performance of intragastric fluid homogenized by the antral contraction.Show less >
Show more >Human digestion, a major concern due to the rapid development of nutrition-related chronic diseases,rely apart from enzymatic reactions on homogenization of the gastric content by antral contractions.Although recent CFD studies made it possible to explore the influence of the rheologicalproperties of the gastric content on the efficiency of gastric mixing, this key step is yet far from beingfully understood.ObjectiveThis work aims at discussing the influences of contraction frequency and viscosity of the digestain human gastric mixing by comparison with the mixing efficiency of an innovative soft elastic reactor(SER), that induces mixing by vibration of its wall in a similar way as antral contraction waves(ACWs) promote stomach motility.MethodologyIn this view, the SER mixing curve, recently established by Delaplace et al. (2018) using a dimensionalanalysis approach, was considered in order to determine the flow regime under which thegastric mixing of foods (viscosity ranging from 10-3 to 1 Pa.s) was performedMain findingsIt was shown that depending on the viscosity of the SER/stomach content and the amplitude of penetration/ACWs, the number of strikes/contractions required to achieve homogenization was largelydifferent. Moreover, the operating points of SER and ACWs mixing were close, justifying the comparisonbetween both reactors.ConclusionBased on this, the level of mechanical solicitation provided by human peristalsis was shown to benot as high as expected, and the mixing performance of distal region, confined in laminar regime,was found limited and not only due to mechanical solicitations. Further efforts are needed to investigatethe role of other physiological processes such as gastric secretions and gastric emptying inmixing performance of intragastric fluid homogenized by the antral contraction.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Related reference(s) :
Administrative institution(s) :
Université de Lille
CNRS
INRA
ENSCL
CNRS
INRA
ENSCL
Collections :
Research team(s) :
Processus aux Interfaces et Hygiène des Matériaux (PIHM)
Submission date :
2021-10-05T09:50:48Z
2021-10-05T09:54:08Z
2021-10-05T09:54:08Z