Polydopamine treatment of chitosan nanofibers ...
Type de document :
Article dans une revue scientifique
URL permanente :
Titre :
Polydopamine treatment of chitosan nanofibers for the conception of osteoinductive scaffolds for bone reconstruction
Auteur(s) :
Dimassi, Syrine [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Tabary, Nicolas [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Chai, Feng [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Zobrist, Cedric [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Hornez, Jean-Christophe [Auteur]
Laboratoire des Matériaux Céramiques et Procédés Associés - EA 2443 [LMCPA]
Cazaux, Frederic [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Blanchemain, Nicolas [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Martel, Bernard [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Unité Matériaux et Transformations - UMR 8207 [UMET]
Tabary, Nicolas [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Chai, Feng [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Zobrist, Cedric [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Hornez, Jean-Christophe [Auteur]
Laboratoire des Matériaux Céramiques et Procédés Associés - EA 2443 [LMCPA]
Cazaux, Frederic [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Blanchemain, Nicolas [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Martel, Bernard [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Titre de la revue :
Carbohydrate Polymers
Nom court de la revue :
Carbohydrate Polymers
Pagination :
118774
Éditeur :
Elsevier BV
Date de publication :
2021-10
ISSN :
0144-8617
Mot(s)-clé(s) en anglais :
Electrospinning
Nanofibers
Polydopamine
Scaffolds
Hydroxyapatite
Bone tissue engineering
Nanofibers
Polydopamine
Scaffolds
Hydroxyapatite
Bone tissue engineering
Discipline(s) HAL :
Chimie/Polymères
Résumé en anglais : [en]
We report the influence of treatment time of electrospun chitosan nanofibers (CHT NFs) in dopamine hydrochloride bath (2 mg.mL−1 in 10 mM Tris buffer, pH 8.5) on the extent of the polydopamine (pDA) coating on NFs surface. ...
Lire la suite >We report the influence of treatment time of electrospun chitosan nanofibers (CHT NFs) in dopamine hydrochloride bath (2 mg.mL−1 in 10 mM Tris buffer, pH 8.5) on the extent of the polydopamine (pDA) coating on NFs surface. The reaction was characterized by FTIR and SEM analysis and the cytocompatibility of the scaffolds toward MT3C3-E1 cells was assessed. Biomimetic deposition of hydroxyapatite (HA) in 1.5xSBF batch was investigated by SEM-EDS and XRD. Samples treated in dopamine bath during 2 h promoted the structural stability of NFs in PBS, provided optimal cytocompatibility and induced the in vitro biomineralization from 6 days in 1.5xSBF. The XRD and SEM-EDS investigations confirmed formation of spherical-shaped particles composed of apatitic phase. Finally, this study shows that these NFs-pDA scaffolds prepared in the optimal experimental conditions defined here are promising candidates for application as osteoinductive scaffolds for bone regeneration applied to orthopedic and dental applications.Lire moins >
Lire la suite >We report the influence of treatment time of electrospun chitosan nanofibers (CHT NFs) in dopamine hydrochloride bath (2 mg.mL−1 in 10 mM Tris buffer, pH 8.5) on the extent of the polydopamine (pDA) coating on NFs surface. The reaction was characterized by FTIR and SEM analysis and the cytocompatibility of the scaffolds toward MT3C3-E1 cells was assessed. Biomimetic deposition of hydroxyapatite (HA) in 1.5xSBF batch was investigated by SEM-EDS and XRD. Samples treated in dopamine bath during 2 h promoted the structural stability of NFs in PBS, provided optimal cytocompatibility and induced the in vitro biomineralization from 6 days in 1.5xSBF. The XRD and SEM-EDS investigations confirmed formation of spherical-shaped particles composed of apatitic phase. Finally, this study shows that these NFs-pDA scaffolds prepared in the optimal experimental conditions defined here are promising candidates for application as osteoinductive scaffolds for bone regeneration applied to orthopedic and dental applications.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Non spécifiée
Établissement(s) :
Université de Lille
CNRS
INRA
ENSCL
CNRS
INRA
ENSCL
Collections :
Équipe(s) de recherche :
Ingénierie des Systèmes Polymères
Date de dépôt :
2021-10-26T06:56:51Z
2021-10-26T07:03:11Z
2021-10-26T07:08:50Z
2021-10-27T06:18:11Z
2021-10-26T07:03:11Z
2021-10-26T07:08:50Z
2021-10-27T06:18:11Z