How to improve the chemical disinfection ...
Document type :
Article dans une revue scientifique: Article original
Permalink :
Title :
How to improve the chemical disinfection of contaminated surfaces by viruses, bacteria and fungus?
Author(s) :
Leclercq, Loïc [Auteur]
Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
Nardello-Rataj, Véronique [Auteur]
Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181

Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
Nardello-Rataj, Véronique [Auteur]

Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
Journal title :
European Journal of Pharmaceutical Sciences
Abbreviated title :
European Journal of Pharmaceutical Sciences
Volume number :
155
Pages :
105559
Publisher :
Elsevier
Publication date :
2020-12-01
ISSN :
0928-0987
English keyword(s) :
Di-n-decyldimethylammonium chloride
Dodecyloctaglycol
Cyclodextrins
Virus inactivation
Membrane interaction
Lipid extraction
Synergistic Formulation
Dodecyloctaglycol
Cyclodextrins
Virus inactivation
Membrane interaction
Lipid extraction
Synergistic Formulation
HAL domain(s) :
Chimie/Chimie organique
English abstract : [en]
In response to the current pandemic situation, we present the development of an effective virucidal and biocidal solution to prevent from the spread of infectious diseases through contact with contaminated surfaces. The ...
Show more >In response to the current pandemic situation, we present the development of an effective virucidal and biocidal solution to prevent from the spread of infectious diseases through contact with contaminated surfaces. The disinfectants, based on equimolar mixtures of didecyldimethylammonium chloride ([DiC10][Cl]), dodecyloctaglycol (C12E8), and cyclodextrin (CD), show synergistic effects against enveloped viruses (RSV, HSV-1, VACV) and fungi (C. albicans), and additive responses against bacteria (P. aeruginosa). These synergistic mixtures could then be highly helpful for prevention of respiratory illnesses, since a boosted activity allows: (i) a faster eradication of pathogens, (ii) a shorter contact time, and (iii) a complete and broad-spectrum eradication to avoid spread of resistant strains (including bacteria and fungi).Show less >
Show more >In response to the current pandemic situation, we present the development of an effective virucidal and biocidal solution to prevent from the spread of infectious diseases through contact with contaminated surfaces. The disinfectants, based on equimolar mixtures of didecyldimethylammonium chloride ([DiC10][Cl]), dodecyloctaglycol (C12E8), and cyclodextrin (CD), show synergistic effects against enveloped viruses (RSV, HSV-1, VACV) and fungi (C. albicans), and additive responses against bacteria (P. aeruginosa). These synergistic mixtures could then be highly helpful for prevention of respiratory illnesses, since a boosted activity allows: (i) a faster eradication of pathogens, (ii) a shorter contact time, and (iii) a complete and broad-spectrum eradication to avoid spread of resistant strains (including bacteria and fungi).Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Other project(s) or funding source(s) :
Chevreul Institute (FR 2638)
Ministère de l'Enseignement Supérieur et de la Recherche
FEDER
Région Hauts de France
Ministère de l'Enseignement Supérieur et de la Recherche
FEDER
Région Hauts de France
Administrative institution(s) :
CNRS
Centrale Lille
ENSCL
Univ. Artois
Université de Lille
Centrale Lille
ENSCL
Univ. Artois
Université de Lille
Collections :
Research team(s) :
Colloïdes catalyse oxydation (CÏSCO)
Submission date :
2021-12-08T09:52:42Z
2022-03-01T16:19:02Z
2023-12-14T19:04:22Z
2022-03-01T16:19:02Z
2023-12-14T19:04:22Z
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