Title :

Influence of puffing conditions on the carbonyl composition of e-cigarette aerosols

Author(s) :

Beauval, Nicolas [Auteur]
Département Sciences de l'Atmosphère et Génie de l'Environnement [SAGE]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
532166|||Ecole nationale supérieure Mines-Télécom Lille Douai [IMT Lille Douai] (OLD)
Verriele, Marie [Auteur]
Ecole nationale supérieure Mines-Télécom Lille Douai [IMT Lille Douai]
Garat, Anne [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
Fronval, Isabelle [Auteur]
Ecole nationale supérieure Mines-Télécom Lille Douai [IMT Lille Douai]
Dusautoir, Romain [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Anthérieu, Sébastien [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
Garçon, Guillaume [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
Lo-Guidice, Jean-Marc [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Allorge, Delphine [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
Locoge, Nadine [Auteur]
Ecole nationale supérieure Mines-Télécom Lille Douai [IMT Nord Europe]

Journal title :

International journal of hygiene and environmental health

Abbreviated title :

Int J Hyg Environ Health

Volume number :

222

Pages :

136-146

Publisher :

Elsevier

Publication date :

2018-09-13

ISSN :

1618-131X

English keyword(s) :

Smoking machine
Puffing regimen
Electronic cigarette
E-vapor
Carbonyls

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Owing to their harmful effects on human health, the presence of carbonyl compounds in e-cigarette aerosols raises concerns. To date, the reported concentration levels in e-vapors vary greatly between studies and several ...
Show more >Owing to their harmful effects on human health, the presence of carbonyl compounds in e-cigarette aerosols raises concerns. To date, the reported concentration levels in e-vapors vary greatly between studies and several factors that markedly influence carbonyl emission during vaping have been highlighted including the heating temperature, the power supply, the device architecture, the filling level of the tank and the main e-liquid constituents. This study investigated the impact of puffing regimen parameters on the carbonyl composition of e-cigarette aerosols with the aim of: (1) better estimating the variability of carbonyl emissions depending on puffing conditions; (2) highlighting puffing profiles that increase the exposure to carbonyls; and (3) estimating to what extent puffing topography could be implied in the variability of carbonyl concentrations reported in the current literature. E-vapors from a single e-liquid were generated from two e-cigarette models with a smoking machine. A total of 7 different puffing regimens were used to individually study the influence of the puff volume, duration and frequency. Carbonyls were collected by DNPH cartridges and analysed by HPLC-UV. E-liquid consumption and e-vapor temperature were also monitored. E-vapor concentrations of formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde and methylglyoxal were affected, sometimes differently, by the modification of the puffing regimen, as well as by the e-cigarette model. For example, formaldehyde concentration ranged from 20 to 255 ng/puff depending on the puffing conditions. The results of principal component analyses, applied to the concentration data sets for the 6 carbonyls, suggest that the studied parameters interact and highlight some "carbonyl-emitting" combinations of concern (e-cigarette model/puffing regimen). However, the highest concentrations measured in the present study remain far lower than those observed in conventional cigarette mainstream smoke. This study confirms that the chosen puffing regimen contributes a part of the observed variability in the carbonyl levels reported in the scientific literature, hampering comparisons between studies and making interpretation difficult. Thus, harmonized and realistic protocols for the assessment of e-cigarette toxicity by physicochemical or experimental approaches are clearly needed.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Submission date :

2022-02-02T10:23:48Z
2024-02-14T10:27:06Z
2024-04-19T15:09:45Z