Knockout of receptor for advanced glycation ...
Document type :
Article dans une revue scientifique: Article original
DOI :
PMID :
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Title :
Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions
Author(s) :
Teissier, Thibault [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Lille Inflammation Research International Center (LIRIC) - U995
Quersin, Valentine [Auteur]
Gnemmi, Viviane [Auteur]
Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer (JPArc) - U1172
Daroux, Maite [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Howsam, Michael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Delguste, Florian [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lemoine, Cecile [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Fradin, Chantal [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Schmidt, Ann-Marie [Auteur]
Cauffiez, Christelle [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Brousseau, Thierry [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Glowacki, Francois [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Tessier, Frederic J. [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Boulanger, Eric [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Frimat, Marie [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Lille Inflammation Research International Center (LIRIC) - U995
Quersin, Valentine [Auteur]
Gnemmi, Viviane [Auteur]
Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer (JPArc) - U1172
Daroux, Maite [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Howsam, Michael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Delguste, Florian [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lemoine, Cecile [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Fradin, Chantal [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Schmidt, Ann-Marie [Auteur]
Cauffiez, Christelle [Auteur]
171461|||Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS] (VALID)
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Brousseau, Thierry [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Glowacki, Francois [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Tessier, Frederic J. [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Boulanger, Eric [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Frimat, Marie [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Journal title :
Aging Cell
Abbreviated title :
Aging Cell
Pages :
e12850
Publisher :
Wiley
Publication date :
2019-02-22
ISSN :
1474-9726
Keyword(s) :
amyloidosis
renal aging
receptor for AGEs
nephrosclerosis
chronic kidney disease
advanced glycation end-products
renal aging
receptor for AGEs
nephrosclerosis
chronic kidney disease
advanced glycation end-products
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Pro-aging effects of endogenous advanced glycation end-products (AGEs) have been reported, and there is increasing interest in the pro-inflammatory and -fibrotic effects of their binding to RAGE (the main AGE receptor). ...
Show more >Pro-aging effects of endogenous advanced glycation end-products (AGEs) have been reported, and there is increasing interest in the pro-inflammatory and -fibrotic effects of their binding to RAGE (the main AGE receptor). The role of dietary AGEs in aging remains ill-defined, but the predominantly renal accumulation of dietary carboxymethyllysine (CML) suggests the kidneys may be particularly affected. We studied the impact of RAGE invalidation and a CML-enriched diet on renal aging. Two-month-old male, wild-type (WT) and RAGE-/-food-/--/--/--/--/-Show less >
Show more >Pro-aging effects of endogenous advanced glycation end-products (AGEs) have been reported, and there is increasing interest in the pro-inflammatory and -fibrotic effects of their binding to RAGE (the main AGE receptor). The role of dietary AGEs in aging remains ill-defined, but the predominantly renal accumulation of dietary carboxymethyllysine (CML) suggests the kidneys may be particularly affected. We studied the impact of RAGE invalidation and a CML-enriched diet on renal aging. Two-month-old male, wild-type (WT) and RAGE-/-food-/--/--/--/--/-Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Institut Pasteur de Lille
Université de Lille
CNRS
Inserm
Institut Pasteur de Lille
Université de Lille
Collections :
Submission date :
2022-02-02T10:23:53Z
2024-02-28T11:04:19Z
2024-02-28T11:04:19Z
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