Title :

Does exposure to inflammatory particles modify the pattern of anion in exhaled breath condensate?

Author(s) :

Sauvain, Jean-Jacques [Auteur]
Centre universitaire de médecine générale et santé publique [Unisanté]
Edme, Jean-Louis [Auteur]
IMPact de l’Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Wild, Pascal [Auteur]
Centre universitaire de médecine générale et santé publique [Unisanté]
Suarez, Guillaume [Auteur]
Centre universitaire de médecine générale et santé publique [Unisanté]
De Paula Alvez Bezerra, Olivia Maria [Auteur]
Universidade Federal de Ouro Preto [UFOP]
Talvani, Andre [Auteur]
Universidade Federal de Ouro Preto [UFOP]
Algranti, Eduardo [Auteur]
Fundacentro
Carneiro, Ana Paula Scalio [Auteur]
Universidade Federal de Minas Gerais = Federal University of Minas Gerais [Belo Horizonte, Brazil] [UFMG]
Chérot-Kornobis, Nathalie [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Sobaszek, Annie [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Hulo, Sebastien [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Journal title :

Journal of Breath Research

Abbreviated title :

J Breath Res

Volume number :

14

Pages :

026005

Publisher :

IOP Science

Publication date :

2020-02-14

ISSN :

1752-7163

English keyword(s) :

exhaled breath condensate
ion chromatography
metabolism
soapstone
quartz
small chain fatty acids

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or ...
Show more >Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or obesity are now emerging in the literature. Collection of exhaled breath condensate (EBC) is an appealing non-invasive technique to sample pulmonary fluids. This hypothesis-generating study aims to (1) validate an ion chromatography method allowing the robust determination of different metabolism-related molecules (lactate, formate, acetate, propionate, butyrate, pyruvate, nitrite, nitrate) in EBC; (2) apply this method to EBC samples collected from workers exposed to quartz (a known inflammatory particle), to soapstone (a less inflammatory particle than quartz), as well as to controls. A multi-compound standard solution was used to determine the linearity range, detection limit, repeatability and bias from spiked EBC. The biological samples were injected without further treatment into an ion chromatograph with a conductivity detector. RTube®Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Other project(s) or funding source(s) :

Action en Région de Coopération Universitaire et Scientifique’ (Programme ARCUS, a partnership between France and Brazil)
Fundação de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)

Administrative institution(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Submission date :

2022-02-02T10:24:25Z
2024-02-20T12:02:40Z