Extracellular vesicles as actors in the air pollution related cardiopulmonary diseases

Alkoussa, Stephanie; Hulo, Sebastien; Courcot, Dominique; Billet, Sylvain; Martin, Perrine J.

Type de document :

Article dans une revue scientifique: Article original

DOI :

10.1080/10408444.2020.1763252

PMID :

32500824

URL permanente :

http://hdl.handle.net/20.500.12210/59750

Titre :

Extracellular vesicles as actors in the air pollution related cardiopulmonary diseases

Auteur(s) :

Alkoussa, Stephanie [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Hulo, Sebastien [Auteur]

IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Courcot, Dominique [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Billet, Sylvain [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Martin, Perrine J. [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]

Titre de la revue :

Critical reviews in toxicology

Nom court de la revue :

Crit. Rev. Toxicol.

Numéro :

Pagination :

1-22

Éditeur :

Taylor & Francis Online

Date de publication :

2020-06-05

ISSN :

1547-6898

Mot(s)-clé(s) en anglais :

air pollutants
particulate matter
lung cancer
COPD
cardiopulmonary diseases
cigarette smoke

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Many associations were reported between air pollution and daily mortality rates for cardiopulmonary diseases. Humans are exposed to a mixture of oxidizing gases and particles, both anthropogenic and natural. Exposure to ...
Lire la suite >Many associations were reported between air pollution and daily mortality rates for cardiopulmonary diseases. Humans are exposed to a mixture of oxidizing gases and particles, both anthropogenic and natural. Exposure to air toxics causes or exacerbates cardiovascular damages and respiratory diseases. Numerous studies have identified the induction of oxidative stress and sustained inflammatory response as among the main known underlying pathophysiological mechanisms of air pollutants. More recently, the relationship between these mechanisms of action and the secretion of extracellular vesicles (EVs) by lung cells has been revealed. EVs have been shown to be important mediators of cellular communication in the body. The purpose of this review is to first recall the main air pollutants. Then, the cardiopulmonary diseases caused by exposure to air pollution and the pathophysiological mechanisms are presented before showing, through an exhaustive review of the literature, the involvement of EVs in the toxicity of air pollutants and the initiation of cardiopulmonary diseases.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Date de dépôt :

2022-02-02T10:24:36Z
2024-02-15T09:28:50Z
2024-03-13T10:32:21Z

Fichiers

Alkoussa et al.pdf
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Historique des modifications

Numéro de version	Lien	Date de modification
3	20.500.12210/59750*	2024-03-13T10:31:23Z
2	20.500.12210/59750.2	2024-02-15T09:24:29Z
1	20.500.12210/59750.1	2022-02-02T10:24:36Z

*Version sélectionnée

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