Extracellular vesicles as actors in the ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Extracellular vesicles as actors in the air pollution related cardiopulmonary diseases
Auteur(s) :
Alkoussa, Stephanie [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Hulo, Sebastien [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Courcot, Dominique [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Billet, Sylvain [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Martin, Perrine J. [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Hulo, Sebastien [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Courcot, Dominique [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Billet, Sylvain [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Martin, Perrine J. [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Titre de la revue :
Critical reviews in toxicology
Nom court de la revue :
Crit. Rev. Toxicol.
Numéro :
50
Pagination :
1-22
Éditeur :
Taylor & Francis Online
Date de publication :
2020-06-05
ISSN :
1547-6898
Mot(s)-clé(s) en anglais :
air pollutants
particulate matter
lung cancer
COPD
cardiopulmonary diseases
cigarette smoke
particulate matter
lung cancer
COPD
cardiopulmonary diseases
cigarette smoke
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Many associations were reported between air pollution and daily mortality rates for cardiopulmonary diseases. Humans are exposed to a mixture of oxidizing gases and particles, both anthropogenic and natural. Exposure to ...
Lire la suite >Many associations were reported between air pollution and daily mortality rates for cardiopulmonary diseases. Humans are exposed to a mixture of oxidizing gases and particles, both anthropogenic and natural. Exposure to air toxics causes or exacerbates cardiovascular damages and respiratory diseases. Numerous studies have identified the induction of oxidative stress and sustained inflammatory response as among the main known underlying pathophysiological mechanisms of air pollutants. More recently, the relationship between these mechanisms of action and the secretion of extracellular vesicles (EVs) by lung cells has been revealed. EVs have been shown to be important mediators of cellular communication in the body. The purpose of this review is to first recall the main air pollutants. Then, the cardiopulmonary diseases caused by exposure to air pollution and the pathophysiological mechanisms are presented before showing, through an exhaustive review of the literature, the involvement of EVs in the toxicity of air pollutants and the initiation of cardiopulmonary diseases.Lire moins >
Lire la suite >Many associations were reported between air pollution and daily mortality rates for cardiopulmonary diseases. Humans are exposed to a mixture of oxidizing gases and particles, both anthropogenic and natural. Exposure to air toxics causes or exacerbates cardiovascular damages and respiratory diseases. Numerous studies have identified the induction of oxidative stress and sustained inflammatory response as among the main known underlying pathophysiological mechanisms of air pollutants. More recently, the relationship between these mechanisms of action and the secretion of extracellular vesicles (EVs) by lung cells has been revealed. EVs have been shown to be important mediators of cellular communication in the body. The purpose of this review is to first recall the main air pollutants. Then, the cardiopulmonary diseases caused by exposure to air pollution and the pathophysiological mechanisms are presented before showing, through an exhaustive review of the literature, the involvement of EVs in the toxicity of air pollutants and the initiation of cardiopulmonary diseases.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Institut Pasteur de Lille
Université de Lille
Institut Pasteur de Lille
Université de Lille
Date de dépôt :
2022-02-02T10:24:36Z
2024-02-15T09:28:50Z
2024-03-13T10:32:21Z
2024-02-15T09:28:50Z
2024-03-13T10:32:21Z
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- Alkoussa et al.pdf
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