Title :

Classification of pedicle ossification after maxillofacial reconstruction with bony free flap: an observational study

Author(s) :

Barry, Florent [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Schlund, Matthias [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Raoul, Gwénaël [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Myon, Luc [Auteur]
Ferri, Joel [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Nicot, Romain [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008

Journal title :

Journal of stomatology, oral and maxillofacial surgery

Abbreviated title :

J Stomatol Oral Maxillofac Surg

Volume number :

123

Pages :

228-232

Publication date :

2021-04-09

ISSN :

2468-7855

English keyword(s) :

maxillofacial reconstruction
bony free flap
pedicle calcification
vascular calcification

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

BACKGROUND: Maxillofacial reconstruction with bony free flap is a classical technique. However, pedicle ossification after such reconstruction is a misunderstood complication that is rarely reported in the literature. It ...
Show more >BACKGROUND: Maxillofacial reconstruction with bony free flap is a classical technique. However, pedicle ossification after such reconstruction is a misunderstood complication that is rarely reported in the literature. It is usually manifested as trismus, neck pain, and hard swelling, but it is predominantly asymptomatic and, thus, mainly incidentally discovered at a later stage. The aim of our study is to propose a classification for pedicle ossification based on both radiological features and vascular calcification progression. We also describe a case of metachronous ossification after two fibula free flap procedures. METHODS: Our observational study includes all patients from our unit who underwent maxillofacial reconstruction with bony free flap from 2003 to 2018. We collected all cases of pedicle ossifications identified during the follow-up and described the radiological status of each one to categorise them in different groups and propose a classification scheme for the same. RESULTS: Radiological and histological analysis showed a progressive three-step evolution of pedicle ossification, starting from the media, progressing into the lumen, and then reaching completion in the extravascular region. The final stage was observed in all symptomatic patients. CONCLUSIONS: Pedicle ossification is a progressive process that passes through three successive histological stages that may be associated with factors such as smooth muscle cell phenotype modification [1]. This complication may lead to more severe clinical symptoms and may require surgery for removal of the calcification.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Research team(s) :

U1008

Submission date :

2022-04-13T07:12:04Z
2024-02-21T08:54:17Z