Title :

The evolving landscape of brain metastasis

Author(s) :

Valiente, Manuel [Auteur]
Ahluwalia, Manmeet S. [Auteur]
Boire, Adrienne [Auteur]
Brastianos, Priscilla K. [Auteur]
Goldberg, Sarah B. [Auteur]
Lee, Eudocia Q. [Auteur]
Le Rhun, Emilie [Auteur]
Preusser, Matthias [Auteur]
Winkler, Frank [Auteur]
Soffietti, Riccardo [Auteur]

Journal title :

Trends in cancer

Abbreviated title :

Trends Cancer

Volume number :

4

Pages :

176-196

Publication date :

2018-03-01

ISSN :

2405-8025

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Metastasis, involving the spread of systemic cancer to the brain, results in neurologic disability and death. Current treatments are largely palliative in nature; improved therapeutic approaches represent an unmet clinical ...
Show more >Metastasis, involving the spread of systemic cancer to the brain, results in neurologic disability and death. Current treatments are largely palliative in nature; improved therapeutic approaches represent an unmet clinical need. However, recent experimental and clinical advances challenge the bleak long-term outcome of this disease. Encompassing key recent findings in epidemiology, genetics, microenvironment, leptomeningeal disease, neurocognition, targeted therapy, immunotherapy, and prophylaxis, we review preclinical and clinical studies to provide a comprehensive picture of contemporary research and the management of secondary brain tumors.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

INSERM
Université de Lille

Collections :

• Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Submission date :

2022-06-15T13:57:34Z