• English
    • français
  • Help
  •  | 
  • Contact
  •  | 
  • About
  •  | 
  • Login
  • HAL portal
  •  | 
  • Pages Pro
  • EN
  •  / 
  • FR
View Item 
  •   LillOA Home
  • Liste des unités
  • Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
  • View Item
  •   LillOA Home
  • Liste des unités
  • Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Diagnostic accuracy of nipple aspirate ...
  • BibTeX
  • CSV
  • Excel
  • RIS

Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
DOI :
10.1245/s10434-020-09313-9
PMID :
33165721
Permalink :
http://hdl.handle.net/20.500.12210/75008
Title :
Diagnostic accuracy of nipple aspirate fluid cytology in asymptomatic patients: a meta-analysis and systematic review of the literature
Author(s) :
Jiwa, Natasha [Auteur]
Gandhewar, Rishikesh [Auteur]
Chauhan, Hemali [Auteur]
Ashrafian, Hutan [Auteur]
Kumar, Swathica [Auteur]
Wright, Corrina [Auteur]
Takats, Zoltan [Auteur]
Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Leff, Daniel Richard [Auteur]
Journal title :
Annals of surgical oncology
Abbreviated title :
Ann. Surg. Oncol.
Volume number :
-
Pages :
-
Publication date :
2020-11-09
ISSN :
1068-9265
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
PURPOSE: To calculate the diagnostic accuracy of nipple aspirate fluid (NAF) cytology. BACKGROUND: Evaluation of NAF cytology in asymptomatic patients conceptually offers a non-invasive method for either screening for ...
Show more >
PURPOSE: To calculate the diagnostic accuracy of nipple aspirate fluid (NAF) cytology. BACKGROUND: Evaluation of NAF cytology in asymptomatic patients conceptually offers a non-invasive method for either screening for breast cancer or else predicting or stratifying future cancer risk. METHODS: Studies were identified by performing electronic searches up to August 2019. A meta-analysis was conducted to attain an overall pooled sensitivity and specificity of NAF for breast cancer detection. RESULTS: A search through 938 studies yielded a total of 19 studies. Overall, 9308 patients were examined, with cytology results from 10,147 breasts [age (years), mean +/- SD = 49.73 +/- 4.09 years]. Diagnostic accuracy meta-analysis of NAF revealed a pooled specificity of 0.97 (95% CI 0.97-0.98), and sensitivity of 0.64 (95% CI 0.62-0.66). CONCLUSIONS: The diagnostic accuracy of nipple smear cytology is limited by poor sensitivity. If nipple fluid assessment is to be used for diagnosis, then emerging technologies for fluid biomarker analysis must supersede the current diagnostic accuracy of NAF cytology.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
INSERM
Université de Lille
Collections :
  • Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192
Submission date :
2022-06-15T13:57:52Z
Files
Thumbnail
  • 2020-11-09-s10434-020-09313-9.pdf
  • Version éditeur
  • Open access
  • Access the document
Université de Lille

Mentions légales
Université de Lille © 2017